FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167376203> ?p ?o ?g. }

• W2167376203 endingPage "3086" @default.
• W2167376203 startingPage "3078" @default.
• W2167376203 abstract "Cellular properties of lateral spinal nucleus neurons in the rat L 6 –S 1 spinal cord. Conventional intracellular recordings were made from 26 lateral spinal nucleus (LSN) neurons in slices of L 6 –S 1 spinal cord from 10- to 15-day-old rats. At rest, LSN neurons did not fire spontaneous action potentials. With injection of a positive current pulse, action potentials had an amplitude of 72 ± 7 (SD) mV and duration at half-peak height of 0.75 ± 0.22 ms. Action potentials were followed by an afterpotential. Most LSN neurons (13/17) exhibited only an afterhyperpolarization (AHP); four neurons exhibited both a fast and a slow AHP separated by an afterdepolarization (ADP). For LSN neurons that exhibited only an AHP, a slow ADP could be identified during bath application of apamin (100 nM). Four of 11 LSN neurons showed a postinhibitory rebound (PIR). Two types of PIR were noted, one with high threshold and low amplitude and the other with low threshold and high amplitude. The PIR with high amplitude was partially blocked in 0 mM Ca 2+ /high Mg 2+ (10 mM) recording solution. Repetitive firing properties were examined in 17 LSN neurons. On the basis of the ratio of the slopes between initial instantaneous firing and steady-state firing frequencies, neurons with low spike frequency adaptation (SFA, 8/17) and high SFA (4/17) were identified. In addition, 2/17 LSN neurons exhibited biphasic repetitive firing patterns, which were composed of a fast SFA, delayed excitation, and low SFA; another two neurons showed only delayed excitation. Plateau potentials also were found in two LSN neurons. Dorsal root stimulation revealed that most LSN neurons (12/13) had polysynaptic postsynaptic potentials (PSP); only one neuron exhibited a monosynaptic PSP. Electrical stimulation of the dorsal root evoked prolonged discharges in low SFA neurons and a short discharge in high SFA neurons. Intrinsic properties were modulated by bath application of substance P (SP). Membrane potentials were depolarized in all eight LSN neurons tested, and membrane resistance was either increased ( n = 3) or decreased ( n = 2). Both instantaneous firing and steady-state firing were facilitated by SP. In addition, oscillation of membrane potentials were induced in three LSN neurons. These results demonstrate that LSN neurons exhibit a variety of intrinsic properties, which may significantly contribute to sensory processing, including nociceptive processing." @default.
• W2167376203 created "2016-06-24" @default.
• W2167376203 creator A5042820937 @default.
• W2167376203 creator A5047846623 @default.
• W2167376203 creator A5091188832 @default.
• W2167376203 date "1999-06-01" @default.
• W2167376203 modified "2023-10-17" @default.
• W2167376203 title "Cellular Properties of Lateral Spinal Nucleus Neurons in the Rat L₆–S₁ Spinal Cord" @default.
• W2167376203 cites W1507346881 @default.
• W2167376203 cites W1782765374 @default.
• W2167376203 cites W1889938522 @default.
• W2167376203 cites W1963655114 @default.
• W2167376203 cites W1963831745 @default.
• W2167376203 cites W1965868535 @default.
• W2167376203 cites W1967739579 @default.
• W2167376203 cites W1972504341 @default.
• W2167376203 cites W1984214402 @default.
• W2167376203 cites W1986178615 @default.
• W2167376203 cites W1987075929 @default.
• W2167376203 cites W1987356832 @default.
• W2167376203 cites W1988273041 @default.
• W2167376203 cites W1991648812 @default.
• W2167376203 cites W1995168007 @default.
• W2167376203 cites W2001376072 @default.
• W2167376203 cites W2016695672 @default.
• W2167376203 cites W2019705527 @default.
• W2167376203 cites W2023065608 @default.
• W2167376203 cites W2024291054 @default.
• W2167376203 cites W2025602313 @default.
• W2167376203 cites W2035563326 @default.
• W2167376203 cites W2035845442 @default.
• W2167376203 cites W2035856095 @default.
• W2167376203 cites W2042388609 @default.
• W2167376203 cites W2042431572 @default.
• W2167376203 cites W2042908983 @default.
• W2167376203 cites W2042938481 @default.
• W2167376203 cites W2046004559 @default.
• W2167376203 cites W2049901933 @default.
• W2167376203 cites W2051374458 @default.
• W2167376203 cites W2053824883 @default.
• W2167376203 cites W2061099467 @default.
• W2167376203 cites W2066347302 @default.
• W2167376203 cites W2066526154 @default.
• W2167376203 cites W2076184480 @default.
• W2167376203 cites W2076571327 @default.
• W2167376203 cites W2087938904 @default.
• W2167376203 cites W2092776809 @default.
• W2167376203 cites W2092855048 @default.
• W2167376203 cites W2100419984 @default.
• W2167376203 cites W2124098347 @default.
• W2167376203 cites W2153631269 @default.
• W2167376203 cites W2178459653 @default.
• W2167376203 cites W2202603207 @default.
• W2167376203 cites W2249998679 @default.
• W2167376203 cites W2404205516 @default.
• W2167376203 cites W2410301190 @default.
• W2167376203 cites W2412018249 @default.
• W2167376203 cites W2416055899 @default.
• W2167376203 cites W2417420688 @default.
• W2167376203 cites W2418002253 @default.
• W2167376203 cites W2443717624 @default.
• W2167376203 cites W2469351461 @default.
• W2167376203 cites W4243836117 @default.
• W2167376203 doi "https://doi.org/10.1152/jn.1999.81.6.3078" @default.
• W2167376203 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10368422" @default.
• W2167376203 hasPublicationYear "1999" @default.
• W2167376203 type Work @default.
• W2167376203 sameAs 2167376203 @default.
• W2167376203 citedByCount "19" @default.
• W2167376203 countsByYear W21673762032013 @default.
• W2167376203 countsByYear W21673762032015 @default.
• W2167376203 countsByYear W21673762032017 @default.
• W2167376203 countsByYear W21673762032018 @default.
• W2167376203 countsByYear W21673762032019 @default.
• W2167376203 countsByYear W21673762032020 @default.
• W2167376203 countsByYear W21673762032021 @default.
• W2167376203 crossrefType "journal-article" @default.
• W2167376203 hasAuthorship W2167376203A5042820937 @default.
• W2167376203 hasAuthorship W2167376203A5047846623 @default.
• W2167376203 hasAuthorship W2167376203A5091188832 @default.
• W2167376203 hasConcept C105702510 @default.
• W2167376203 hasConcept C121332964 @default.
• W2167376203 hasConcept C12554922 @default.
• W2167376203 hasConcept C169760540 @default.
• W2167376203 hasConcept C185263204 @default.
• W2167376203 hasConcept C185592680 @default.
• W2167376203 hasConcept C2776919887 @default.
• W2167376203 hasConcept C2780723820 @default.
• W2167376203 hasConcept C2780775167 @default.
• W2167376203 hasConcept C83743174 @default.
• W2167376203 hasConcept C86803240 @default.
• W2167376203 hasConcept C93872552 @default.
• W2167376203 hasConceptScore W2167376203C105702510 @default.
• W2167376203 hasConceptScore W2167376203C121332964 @default.
• W2167376203 hasConceptScore W2167376203C12554922 @default.
• W2167376203 hasConceptScore W2167376203C169760540 @default.
• W2167376203 hasConceptScore W2167376203C185263204 @default.
• W2167376203 hasConceptScore W2167376203C185592680 @default.

• next