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- W2167465511 abstract "Homocysteine (HCY) is a known risk factor for neuronal diseases. We here report that HCY (10–1000 μM) interfered bi-directionally with long-term potentiation (LTP) in hippocampal slices, causing an impairment at concentrations <100 μM, and enhancement ≥500 μM. By comparison, NMDA unidirectionally reduced LTP, whereas l-cysteine led to facilitated LTP. Such HCY-induced alterations in neuronal communication may contribute to cognitive failure in dementia." @default.
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- W2167465511 date "2009-12-28" @default.
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- W2167465511 title "Bi-directional alterations of LTP after acute homocysteine exposure" @default.
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- W2167465511 doi "https://doi.org/10.1016/j.bbr.2009.07.010" @default.
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