FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167472289> ?p ?o ?g. }

• W2167472289 endingPage "73" @default.
• W2167472289 startingPage "47" @default.
• W2167472289 abstract "Sarcomas are rare, mesenchymal tumors of the soft tissue and bone that exhibit a marked heterogeneity in their clinical presentation, biologic behavior, and histologic features. Approximately 10,400 new cases are diagnosed annually, 7800 of which arise from the soft tissues (50–60% of which involve the extremities) and 2600 from bones.1 Although the incidence of extremity sarcomas is similar to that of Hodgkin’s disease, they are responsible for more than twice as many deaths each year. Major advances in the treatment of these tumors have been limited by an inability to accumulate sufficient numbers of similar patients to perform prospective randomized clinical trials with results that can achieve statistical significance. Until the 1970s, surgery and/or radiation therapy was the accepted method for the primary management of most soft-tissue and bone sarcomas of the extremities. However, surgery alone, especially wide resection, was associated with a high incidence of local recurrences. Even when local control was achieved, more than 50% of patients with soft-tissue sarcoma and 80% of patients with skeletal sarcoma (osteogenic and Ewing’s sarcoma) eventually developed distant metastases and died, usually within 2 years.2–11 Systemic chemotherapy was subsequently found to exhibit reproducible anti-tumor effects against these neoplasms. Initially used only in the treatment of metastatic disease, this was later used as a part of combined-modality therapy in the adjuvant (postoperative) setting, and then as preoperative (neoadjuvant, induction) therapy in an attempt to preserve limb function and/or increase long-term survival.2–11 The routes of chemotherapy administration have included intravenous (IV) bolus, continuous IV infusion, and local (regional) drug delivery directly to the tumor via a feeding artery.12" @default.
• W2167472289 created "2016-06-24" @default.
• W2167472289 creator A5050234128 @default.
• W2167472289 creator A5058226099 @default.
• W2167472289 date "2006-02-24" @default.
• W2167472289 modified "2023-10-16" @default.
• W2167472289 title "The Role of Chemotherapy in the Treatment of Bone and Soft-tissue Sarcomas" @default.
• W2167472289 cites W1556264168 @default.
• W2167472289 cites W1606259773 @default.
• W2167472289 cites W170676557 @default.
• W2167472289 cites W1798881598 @default.
• W2167472289 cites W1810454109 @default.
• W2167472289 cites W1822295824 @default.
• W2167472289 cites W1854116296 @default.
• W2167472289 cites W1856961639 @default.
• W2167472289 cites W1857092002 @default.
• W2167472289 cites W1859724961 @default.
• W2167472289 cites W1864208984 @default.
• W2167472289 cites W1876135160 @default.
• W2167472289 cites W1883812557 @default.
• W2167472289 cites W1892579032 @default.
• W2167472289 cites W1902222293 @default.
• W2167472289 cites W1928072155 @default.
• W2167472289 cites W1929606469 @default.
• W2167472289 cites W1946181835 @default.
• W2167472289 cites W1954845453 @default.
• W2167472289 cites W1963552909 @default.
• W2167472289 cites W1964020503 @default.
• W2167472289 cites W1968195674 @default.
• W2167472289 cites W1968499586 @default.
• W2167472289 cites W1968999500 @default.
• W2167472289 cites W1971910575 @default.
• W2167472289 cites W1973158710 @default.
• W2167472289 cites W1973913393 @default.
• W2167472289 cites W1975487499 @default.
• W2167472289 cites W1979832482 @default.
• W2167472289 cites W1981956631 @default.
• W2167472289 cites W1992752045 @default.
• W2167472289 cites W1998191384 @default.
• W2167472289 cites W2000479372 @default.
• W2167472289 cites W2001630588 @default.
• W2167472289 cites W2002215444 @default.
• W2167472289 cites W2003743385 @default.
• W2167472289 cites W2003969422 @default.
• W2167472289 cites W2004118732 @default.
• W2167472289 cites W2005033250 @default.
• W2167472289 cites W2013220351 @default.
• W2167472289 cites W2015639618 @default.
• W2167472289 cites W2018341895 @default.
• W2167472289 cites W2019673751 @default.
• W2167472289 cites W2019970331 @default.
• W2167472289 cites W2020150372 @default.
• W2167472289 cites W2027419421 @default.
• W2167472289 cites W2029751589 @default.
• W2167472289 cites W2034328882 @default.
• W2167472289 cites W2036247878 @default.
• W2167472289 cites W2037385810 @default.
• W2167472289 cites W2045383719 @default.
• W2167472289 cites W2050113647 @default.
• W2167472289 cites W2050352100 @default.
• W2167472289 cites W2051183024 @default.
• W2167472289 cites W2051856631 @default.
• W2167472289 cites W2051992326 @default.
• W2167472289 cites W2053482333 @default.
• W2167472289 cites W2060688081 @default.
• W2167472289 cites W2063759313 @default.
• W2167472289 cites W2065289547 @default.
• W2167472289 cites W2069219181 @default.
• W2167472289 cites W2073442604 @default.
• W2167472289 cites W2077274936 @default.
• W2167472289 cites W2077746558 @default.
• W2167472289 cites W2079088649 @default.
• W2167472289 cites W2082675463 @default.
• W2167472289 cites W2082914423 @default.
• W2167472289 cites W2086628813 @default.
• W2167472289 cites W2088475125 @default.
• W2167472289 cites W2090278741 @default.
• W2167472289 cites W2096691972 @default.
• W2167472289 cites W2097904291 @default.
• W2167472289 cites W2100055648 @default.
• W2167472289 cites W2104953667 @default.
• W2167472289 cites W2105886206 @default.
• W2167472289 cites W2107463183 @default.
• W2167472289 cites W2113211750 @default.
• W2167472289 cites W2116042827 @default.
• W2167472289 cites W2119446689 @default.
• W2167472289 cites W2120243695 @default.
• W2167472289 cites W2131155074 @default.
• W2167472289 cites W2138178697 @default.
• W2167472289 cites W2142136189 @default.
• W2167472289 cites W2152308356 @default.
• W2167472289 cites W2153365867 @default.
• W2167472289 cites W2154027407 @default.
• W2167472289 cites W2156067388 @default.
• W2167472289 cites W2161378536 @default.
• W2167472289 cites W2162889164 @default.
• W2167472289 cites W2163165105 @default.
• W2167472289 cites W2163989427 @default.

• next