FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167474274> ?p ?o ?g. }

• W2167474274 endingPage "1570" @default.
• W2167474274 startingPage "1563" @default.
• W2167474274 abstract "Hepatic arterial chemotherapy for liver metastases of colorectal cancer is still under discussion. Mainly because of the technical complications of this mode of treatment and the lack of a survival benefit in randomized studies. We performed an analysis of hepatic arterial 5-fluorouracil (5-FU) chemotherapy in 145 consecutive patients treated at a single institution.One hundred forty-five patients with inoperable liver metastases from colorectal cancer were included. 5-FU, 1000 mg/m2/day continuous infusion for five days every three weeks, was delivered in the hepatic artery by percutaneous catheter or arterial access device.The response rate was 34% for all patients, 40% in patients with extrahepatic disease, and 15% in patients with i.v. 5-FU-based pretreatment. TTP and OS for all patients were 7.5 and 14.3 months, respectively. In patients with extrahepatic disease or i.v. 5-FU-based pretreatment, OS was significantly shorter compared to patients without extrahepatic disease or 5-FU-based pretreatment (9.7 vs. 19.3 months and 10.1 vs. 17.4 months, respectively), forty-seven percent of patients stopped treatment because of a complication. Complications most often seen in patients with arterial ports were hepatic artery thrombosis (48%) and dislocation of the catheter (22%).The results of our analysis are in line with previous phase III studies. Extrahepatic disease and i.v. 5-FU-based pretreatment were prognostic for reduced OS. The complication rate of hepatic arterial delivery was worrisome. although, no negative impact on survival could be established. There is a strong need for improvement of hepatic arterial delivery methods before further evaluation of hepatic arterial" @default.
• W2167474274 created "2016-06-24" @default.
• W2167474274 creator A5002685158 @default.
• W2167474274 creator A5005395551 @default.
• W2167474274 creator A5022063365 @default.
• W2167474274 creator A5030570166 @default.
• W2167474274 creator A5031437673 @default.
• W2167474274 creator A5034285829 @default.
• W2167474274 creator A5037107233 @default.
• W2167474274 creator A5073129226 @default.
• W2167474274 creator A5090478461 @default.
• W2167474274 date "2000-12-01" @default.
• W2167474274 modified "2023-09-27" @default.
• W2167474274 title "Hepatic arterial 5-fluorouracil in patients with liver metastases of colorectal cancer: Single-centre experience in 145 patients" @default.
• W2167474274 cites W1485041712 @default.
• W2167474274 cites W1823144309 @default.
• W2167474274 cites W1830311297 @default.
• W2167474274 cites W1835268604 @default.
• W2167474274 cites W1861907262 @default.
• W2167474274 cites W1935579689 @default.
• W2167474274 cites W1961040537 @default.
• W2167474274 cites W1971508679 @default.
• W2167474274 cites W1979423262 @default.
• W2167474274 cites W1982472810 @default.
• W2167474274 cites W1986924507 @default.
• W2167474274 cites W1992421431 @default.
• W2167474274 cites W2000841655 @default.
• W2167474274 cites W2006824814 @default.
• W2167474274 cites W2007615142 @default.
• W2167474274 cites W2012217204 @default.
• W2167474274 cites W2024934238 @default.
• W2167474274 cites W2029059845 @default.
• W2167474274 cites W2032146688 @default.
• W2167474274 cites W2043731575 @default.
• W2167474274 cites W2044224410 @default.
• W2167474274 cites W2052845194 @default.
• W2167474274 cites W2075962633 @default.
• W2167474274 cites W2078453319 @default.
• W2167474274 cites W2096122707 @default.
• W2167474274 cites W2122364701 @default.
• W2167474274 cites W2125551462 @default.
• W2167474274 cites W2125892433 @default.
• W2167474274 cites W2128813634 @default.
• W2167474274 cites W2171680834 @default.
• W2167474274 cites W2212365310 @default.
• W2167474274 cites W2395518706 @default.
• W2167474274 cites W2468837473 @default.
• W2167474274 doi "https://doi.org/10.1023/a:1008369520179" @default.
• W2167474274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11205464" @default.
• W2167474274 hasPublicationYear "2000" @default.
• W2167474274 type Work @default.
• W2167474274 sameAs 2167474274 @default.
• W2167474274 citedByCount "18" @default.
• W2167474274 countsByYear W21674742742012 @default.
• W2167474274 countsByYear W21674742742013 @default.
• W2167474274 countsByYear W21674742742014 @default.
• W2167474274 countsByYear W21674742742016 @default.
• W2167474274 crossrefType "journal-article" @default.
• W2167474274 hasAuthorship W2167474274A5002685158 @default.
• W2167474274 hasAuthorship W2167474274A5005395551 @default.
• W2167474274 hasAuthorship W2167474274A5022063365 @default.
• W2167474274 hasAuthorship W2167474274A5030570166 @default.
• W2167474274 hasAuthorship W2167474274A5031437673 @default.
• W2167474274 hasAuthorship W2167474274A5034285829 @default.
• W2167474274 hasAuthorship W2167474274A5037107233 @default.
• W2167474274 hasAuthorship W2167474274A5073129226 @default.
• W2167474274 hasAuthorship W2167474274A5090478461 @default.
• W2167474274 hasBestOaLocation W21674742741 @default.
• W2167474274 hasConcept C121608353 @default.
• W2167474274 hasConcept C126322002 @default.
• W2167474274 hasConcept C141071460 @default.
• W2167474274 hasConcept C2776694085 @default.
• W2167474274 hasConcept C2778405590 @default.
• W2167474274 hasConcept C2780456651 @default.
• W2167474274 hasConcept C2781267111 @default.
• W2167474274 hasConcept C526805850 @default.
• W2167474274 hasConcept C71924100 @default.
• W2167474274 hasConcept C81182388 @default.
• W2167474274 hasConcept C90924648 @default.
• W2167474274 hasConceptScore W2167474274C121608353 @default.
• W2167474274 hasConceptScore W2167474274C126322002 @default.
• W2167474274 hasConceptScore W2167474274C141071460 @default.
• W2167474274 hasConceptScore W2167474274C2776694085 @default.
• W2167474274 hasConceptScore W2167474274C2778405590 @default.
• W2167474274 hasConceptScore W2167474274C2780456651 @default.
• W2167474274 hasConceptScore W2167474274C2781267111 @default.
• W2167474274 hasConceptScore W2167474274C526805850 @default.
• W2167474274 hasConceptScore W2167474274C71924100 @default.
• W2167474274 hasConceptScore W2167474274C81182388 @default.
• W2167474274 hasConceptScore W2167474274C90924648 @default.
• W2167474274 hasIssue "12" @default.
• W2167474274 hasLocation W21674742741 @default.
• W2167474274 hasLocation W21674742742 @default.
• W2167474274 hasOpenAccess W2167474274 @default.
• W2167474274 hasPrimaryLocation W21674742741 @default.
• W2167474274 hasRelatedWork W2032084645 @default.
• W2167474274 hasRelatedWork W2047967234 @default.
• W2167474274 hasRelatedWork W2189014522 @default.

• next