FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167476863> ?p ?o ?g. }

• W2167476863 abstract "Proper management of depression in elderly population would improve the outcome of the disease and reduce its related disability and mortality. Use of memantine with minimal side effects and drug interaction seems reasonable in the elderly but its antidepressant activity is controversial. The aim of the current research is to investigate the effects of add-on memantine during citalopram therapy in elderly patients with depression, in Isfahan.In this double-blind, placebo controlled trial study; elderly patients aged more than 60 years who were recently diagnosed with depression, were enrolled. The selected patients were randomlysplit into two groups, viz. intervention and placebo groups. The intervention was memantine (20 mg daily) or identical placebo plus citalopram for 8 weeks. The severity of depression and quality of life was evaluated using Geriatric Depression Scale (GDS-15), Hamilton Rating Scale for depression (HRSD) and World Health Organization Quality of Life WHOQOL-BREF respectively. The mentioned scores were evaluated at baseline, 4 weeks and 8 weeks, after initiating the trial in two studied groups and compared with each other.28 and 29 patients were studied in the intervention and placebo groups, respectively. Score of GDS-15, HRSD and WHO-QOL-BREF scales at baseline, 4 weeks and 8 weeks, after initiating trial did not change significantly after use of memantine (P > 0.05). There was no significant difference in mean +/- SD of GDS-15, HRSD and WHO-QOL-BREF scales among intervention and placebo groups (P > 0.05).The outcome of this clinical trial did not support the antidepressant effect of add-on memantine in elderly patients with depression receiving citalopram. It is recommended to design further studies considering the limitations of the current study mentioned herein and the effect of memantine with other anti-depressant agents." @default.
• W2167476863 created "2016-06-24" @default.
• W2167476863 creator A5023328726 @default.
• W2167476863 creator A5052560349 @default.
• W2167476863 creator A5058849189 @default.
• W2167476863 creator A5065055618 @default.
• W2167476863 creator A5089053830 @default.
• W2167476863 date "2014-06-01" @default.
• W2167476863 modified "2023-10-15" @default.
• W2167476863 title "Memantine add on to citalopram in elderly patients with depression: A double-blind placebo-controlled study." @default.
• W2167476863 cites W1514982086 @default.
• W2167476863 cites W1524631360 @default.
• W2167476863 cites W1847168837 @default.
• W2167476863 cites W1850125528 @default.
• W2167476863 cites W1921595536 @default.
• W2167476863 cites W1964495258 @default.
• W2167476863 cites W1967545898 @default.
• W2167476863 cites W1984347061 @default.
• W2167476863 cites W1992439492 @default.
• W2167476863 cites W1993254538 @default.
• W2167476863 cites W2006611387 @default.
• W2167476863 cites W2012202426 @default.
• W2167476863 cites W2012382646 @default.
• W2167476863 cites W2023081218 @default.
• W2167476863 cites W2027572751 @default.
• W2167476863 cites W2031231313 @default.
• W2167476863 cites W2034987992 @default.
• W2167476863 cites W2046489639 @default.
• W2167476863 cites W2060920389 @default.
• W2167476863 cites W2079188008 @default.
• W2167476863 cites W2091627651 @default.
• W2167476863 cites W2098815266 @default.
• W2167476863 cites W2109334244 @default.
• W2167476863 cites W2110481328 @default.
• W2167476863 cites W2116570237 @default.
• W2167476863 cites W2132303235 @default.
• W2167476863 cites W2132633462 @default.
• W2167476863 cites W2147654688 @default.
• W2167476863 cites W2148863510 @default.
• W2167476863 cites W2170085655 @default.
• W2167476863 cites W2170790660 @default.
• W2167476863 cites W2404896035 @default.
• W2167476863 cites W3149245474 @default.
• W2167476863 cites W39805860 @default.
• W2167476863 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4155707" @default.
• W2167476863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25197294" @default.
• W2167476863 hasPublicationYear "2014" @default.
• W2167476863 type Work @default.
• W2167476863 sameAs 2167476863 @default.
• W2167476863 citedByCount "8" @default.
• W2167476863 countsByYear W21674768632015 @default.
• W2167476863 countsByYear W21674768632016 @default.
• W2167476863 countsByYear W21674768632017 @default.
• W2167476863 countsByYear W21674768632018 @default.
• W2167476863 countsByYear W21674768632021 @default.
• W2167476863 countsByYear W21674768632022 @default.
• W2167476863 countsByYear W21674768632023 @default.
• W2167476863 crossrefType "journal-article" @default.
• W2167476863 hasAuthorship W2167476863A5023328726 @default.
• W2167476863 hasAuthorship W2167476863A5052560349 @default.
• W2167476863 hasAuthorship W2167476863A5058849189 @default.
• W2167476863 hasAuthorship W2167476863A5065055618 @default.
• W2167476863 hasAuthorship W2167476863A5089053830 @default.
• W2167476863 hasConcept C118552586 @default.
• W2167476863 hasConcept C126322002 @default.
• W2167476863 hasConcept C138496976 @default.
• W2167476863 hasConcept C139719470 @default.
• W2167476863 hasConcept C142724271 @default.
• W2167476863 hasConcept C15744967 @default.
• W2167476863 hasConcept C159110408 @default.
• W2167476863 hasConcept C162324750 @default.
• W2167476863 hasConcept C168563851 @default.
• W2167476863 hasConcept C1862650 @default.
• W2167476863 hasConcept C202061045 @default.
• W2167476863 hasConcept C204787440 @default.
• W2167476863 hasConcept C27081682 @default.
• W2167476863 hasConcept C2776760841 @default.
• W2167476863 hasConcept C2776867660 @default.
• W2167476863 hasConcept C2777490545 @default.
• W2167476863 hasConcept C2779134260 @default.
• W2167476863 hasConcept C2779177272 @default.
• W2167476863 hasConcept C2779483572 @default.
• W2167476863 hasConcept C2779484449 @default.
• W2167476863 hasConcept C2779951463 @default.
• W2167476863 hasConcept C2781161787 @default.
• W2167476863 hasConcept C2991744798 @default.
• W2167476863 hasConcept C3019858935 @default.
• W2167476863 hasConcept C558461103 @default.
• W2167476863 hasConcept C71924100 @default.
• W2167476863 hasConcept C83849319 @default.
• W2167476863 hasConceptScore W2167476863C118552586 @default.
• W2167476863 hasConceptScore W2167476863C126322002 @default.
• W2167476863 hasConceptScore W2167476863C138496976 @default.
• W2167476863 hasConceptScore W2167476863C139719470 @default.
• W2167476863 hasConceptScore W2167476863C142724271 @default.
• W2167476863 hasConceptScore W2167476863C15744967 @default.
• W2167476863 hasConceptScore W2167476863C159110408 @default.
• W2167476863 hasConceptScore W2167476863C162324750 @default.
• W2167476863 hasConceptScore W2167476863C168563851 @default.
• W2167476863 hasConceptScore W2167476863C1862650 @default.

• next