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- W2167495364 abstract "Background: Hepatitis C virus (HCV) is one of the major etiological agents of chronic viral hepatitis. It of- ten progresses to chronic hepatitis, cirrhosis and hepatocellular carcinoma. Interleukin-8 (IL-8) is a cytokine involved in the cellular response to inflammation, being a powerful chemoattractant for neutrophils. This work aimed to estimate serum level of IL-8 in chronic liver disease (CLD) patients due to HCV. Methods: This study included fifty CLD patients due to HCV and fifty controls. They were subjected to history taking, liver biopsy, liver function tests and other laboratory tests. Serum IL-8 had been assayed by IMMULITE® 1000 IL-8. Results: Serum IL-8 levels were significantly higher in chronic HCV patients compared to controls. Non-responders had higher baseline interleukin-8 levels than responders. Conclusions: Serum IL-8 is a significant predictor for interferon/ribavirin therapy response in studied chronic HCV patients. Responders are found to have lower pretreatment serum IL-8 than non-responders." @default.
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- W2167495364 date "2011-10-01" @default.
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- W2167495364 title "A Study of Serum Interlukin-8 Level in Chronic Hepatitis C Infected Patients in Suez Canal Area" @default.
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- W2167495364 doi "https://doi.org/10.15373/2249555x/july2013/16" @default.
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