Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167499835> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2167499835 endingPage "10114" @default.
- W2167499835 startingPage "10109" @default.
- W2167499835 abstract "The polymerization of individual RecA-DNA filaments, containing either single-stranded or double-stranded DNA, was followed in real time, and their mechanical properties were characterized with force-measuring laser tweezers. It was found that the stretch modulus of a filament is dominated by its (central) DNA component, while its bending rigidity is controlled by its (eccentric) protein component. The longitudinal stiffness of DNA increases 6- to 12-fold when the DNA is contained in the protein helix. Both the stretch modulus and the bending rigidity of a fiber change in the presence of various nucleotide cofactors-e.g., [gamma-thio]ATP, ATP, and ADP-indicating a substantial re-arrangement of spatial relationships between the nucleic acid and the protein scaffold. In particular, when complexed with ATP, a fiber becomes twice as extensible as a [gamma-thio]ATP fiber, suggesting that 32% of the DNA-binding sites have been released in its core. Such release may enable easy rotation of the DNA within the protein helix or slippage of the DNA through the center of the protein helix." @default.
- W2167499835 created "2016-06-24" @default.
- W2167499835 creator A5010743284 @default.
- W2167499835 creator A5055977616 @default.
- W2167499835 creator A5078718188 @default.
- W2167499835 date "1999-08-31" @default.
- W2167499835 modified "2023-09-25" @default.
- W2167499835 title "Polymerization and mechanical properties of single RecA–DNA filaments" @default.
- W2167499835 cites W1489743769 @default.
- W2167499835 cites W1492465042 @default.
- W2167499835 cites W1590140535 @default.
- W2167499835 cites W1607200676 @default.
- W2167499835 cites W1965513685 @default.
- W2167499835 cites W1969245469 @default.
- W2167499835 cites W1982003972 @default.
- W2167499835 cites W1987646007 @default.
- W2167499835 cites W2021984369 @default.
- W2167499835 cites W2036475903 @default.
- W2167499835 cites W2044678617 @default.
- W2167499835 cites W2053373192 @default.
- W2167499835 cites W2081407528 @default.
- W2167499835 cites W2088209275 @default.
- W2167499835 cites W2094049981 @default.
- W2167499835 cites W2104618027 @default.
- W2167499835 cites W2149374899 @default.
- W2167499835 cites W2159075866 @default.
- W2167499835 cites W2174338827 @default.
- W2167499835 cites W4234689925 @default.
- W2167499835 doi "https://doi.org/10.1073/pnas.96.18.10109" @default.
- W2167499835 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/17850" @default.
- W2167499835 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10468570" @default.
- W2167499835 hasPublicationYear "1999" @default.
- W2167499835 type Work @default.
- W2167499835 sameAs 2167499835 @default.
- W2167499835 citedByCount "211" @default.
- W2167499835 countsByYear W21674998352012 @default.
- W2167499835 countsByYear W21674998352013 @default.
- W2167499835 countsByYear W21674998352014 @default.
- W2167499835 countsByYear W21674998352015 @default.
- W2167499835 countsByYear W21674998352016 @default.
- W2167499835 countsByYear W21674998352017 @default.
- W2167499835 countsByYear W21674998352018 @default.
- W2167499835 countsByYear W21674998352019 @default.
- W2167499835 countsByYear W21674998352020 @default.
- W2167499835 countsByYear W21674998352021 @default.
- W2167499835 countsByYear W21674998352022 @default.
- W2167499835 countsByYear W21674998352023 @default.
- W2167499835 crossrefType "journal-article" @default.
- W2167499835 hasAuthorship W2167499835A5010743284 @default.
- W2167499835 hasAuthorship W2167499835A5055977616 @default.
- W2167499835 hasAuthorship W2167499835A5078718188 @default.
- W2167499835 hasBestOaLocation W21674998352 @default.
- W2167499835 hasConcept C12554922 @default.
- W2167499835 hasConcept C14228908 @default.
- W2167499835 hasConcept C185592680 @default.
- W2167499835 hasConcept C18903297 @default.
- W2167499835 hasConcept C2778530040 @default.
- W2167499835 hasConcept C2779965526 @default.
- W2167499835 hasConcept C552990157 @default.
- W2167499835 hasConcept C55493867 @default.
- W2167499835 hasConcept C8010536 @default.
- W2167499835 hasConcept C86803240 @default.
- W2167499835 hasConceptScore W2167499835C12554922 @default.
- W2167499835 hasConceptScore W2167499835C14228908 @default.
- W2167499835 hasConceptScore W2167499835C185592680 @default.
- W2167499835 hasConceptScore W2167499835C18903297 @default.
- W2167499835 hasConceptScore W2167499835C2778530040 @default.
- W2167499835 hasConceptScore W2167499835C2779965526 @default.
- W2167499835 hasConceptScore W2167499835C552990157 @default.
- W2167499835 hasConceptScore W2167499835C55493867 @default.
- W2167499835 hasConceptScore W2167499835C8010536 @default.
- W2167499835 hasConceptScore W2167499835C86803240 @default.
- W2167499835 hasIssue "18" @default.
- W2167499835 hasLocation W21674998351 @default.
- W2167499835 hasLocation W21674998352 @default.
- W2167499835 hasLocation W21674998353 @default.
- W2167499835 hasLocation W21674998354 @default.
- W2167499835 hasOpenAccess W2167499835 @default.
- W2167499835 hasPrimaryLocation W21674998351 @default.
- W2167499835 hasRelatedWork W1492465042 @default.
- W2167499835 hasRelatedWork W1971269275 @default.
- W2167499835 hasRelatedWork W1990010457 @default.
- W2167499835 hasRelatedWork W2012016974 @default.
- W2167499835 hasRelatedWork W2027174789 @default.
- W2167499835 hasRelatedWork W2037145079 @default.
- W2167499835 hasRelatedWork W2050871669 @default.
- W2167499835 hasRelatedWork W2116711646 @default.
- W2167499835 hasRelatedWork W2125844242 @default.
- W2167499835 hasRelatedWork W2152393922 @default.
- W2167499835 hasVolume "96" @default.
- W2167499835 isParatext "false" @default.
- W2167499835 isRetracted "false" @default.
- W2167499835 magId "2167499835" @default.
- W2167499835 workType "article" @default.