FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167566285> ?p ?o ?g. }

• W2167566285 endingPage "220" @default.
• W2167566285 startingPage "213" @default.
• W2167566285 abstract "Recently discovered macrocyclic carbon suboxide (MCS) factors with the general formula (C(3)O(2))(n) were found to strongly inhibit rabbit and rat Na,K-ATPase as well as SR Ca-ATPase. Highly active MCS factors were obtained by a base/acid treatment of their lipophilic precursor isolated from plants. In the ESI-MS spectra, the dominant molar mass ion of 431 Da corresponds to a 1:1 complex of the carbon suboxide hexamer (n=6; M(r)=408 Da) with a Na(+) ion. Additional mass ions identified in positive and negative ion mode were assigned as complexes of the MCS hexamer (n=6) and octamer (n=8) with Na(+) or with TFA(-) in various ratios. The dominant mass ion values of these active MCS factors from plants are also found in mass spectra of previously described endogenous digitalis-like factors (EDLF) from animals. This would suggest that ubiquitously distributed MCS factors may function as putative endogenous regulatory substances of Na,K-ATPase and possibly of other ATPases. With the symmetric display of several equivalent carbonyl or hydroxy groups, the structure of MCS factors is particularly suited for interactions with proteins and other bio-molecules. This could explain the high biological activity and the unusual properties of the MCS factors." @default.
• W2167566285 created "2016-06-24" @default.
• W2167566285 creator A5001565953 @default.
• W2167566285 creator A5007237100 @default.
• W2167566285 creator A5042847129 @default.
• W2167566285 creator A5065040807 @default.
• W2167566285 creator A5065468362 @default.
• W2167566285 date "2002-12-01" @default.
• W2167566285 modified "2023-09-27" @default.
• W2167566285 title "Characterization of the macrocyclic carbon suboxide factors as potent Na,K-ATPase and SR Ca-ATPase inhibitors" @default.
• W2167566285 cites W1506387083 @default.
• W2167566285 cites W1508102251 @default.
• W2167566285 cites W1548022389 @default.
• W2167566285 cites W1982448040 @default.
• W2167566285 cites W1991548431 @default.
• W2167566285 cites W1996656734 @default.
• W2167566285 cites W2004011009 @default.
• W2167566285 cites W2036898967 @default.
• W2167566285 cites W2056566634 @default.
• W2167566285 cites W2057083888 @default.
• W2167566285 cites W2057119319 @default.
• W2167566285 cites W2068410221 @default.
• W2167566285 cites W2070947674 @default.
• W2167566285 cites W2078713240 @default.
• W2167566285 cites W2082515120 @default.
• W2167566285 cites W2093166155 @default.
• W2167566285 cites W2139882317 @default.
• W2167566285 cites W2142367518 @default.
• W2167566285 cites W2144523428 @default.
• W2167566285 cites W2156612859 @default.
• W2167566285 cites W2159239277 @default.
• W2167566285 cites W2487965214 @default.
• W2167566285 cites W944878829 @default.
• W2167566285 doi "https://doi.org/10.1016/s0005-2736(02)00609-0" @default.
• W2167566285 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12488055" @default.
• W2167566285 hasPublicationYear "2002" @default.
• W2167566285 type Work @default.
• W2167566285 sameAs 2167566285 @default.
• W2167566285 citedByCount "12" @default.
• W2167566285 countsByYear W21675662852013 @default.
• W2167566285 countsByYear W21675662852015 @default.
• W2167566285 countsByYear W21675662852018 @default.
• W2167566285 countsByYear W21675662852020 @default.
• W2167566285 countsByYear W21675662852021 @default.
• W2167566285 countsByYear W21675662852022 @default.
• W2167566285 countsByYear W21675662852023 @default.
• W2167566285 crossrefType "journal-article" @default.
• W2167566285 hasAuthorship W2167566285A5001565953 @default.
• W2167566285 hasAuthorship W2167566285A5007237100 @default.
• W2167566285 hasAuthorship W2167566285A5042847129 @default.
• W2167566285 hasAuthorship W2167566285A5065040807 @default.
• W2167566285 hasAuthorship W2167566285A5065468362 @default.
• W2167566285 hasBestOaLocation W21675662852 @default.
• W2167566285 hasConcept C104317684 @default.
• W2167566285 hasConcept C145148216 @default.
• W2167566285 hasConcept C173681060 @default.
• W2167566285 hasConcept C178790620 @default.
• W2167566285 hasConcept C181199279 @default.
• W2167566285 hasConcept C185592680 @default.
• W2167566285 hasConcept C189754071 @default.
• W2167566285 hasConcept C23265538 @default.
• W2167566285 hasConcept C40325409 @default.
• W2167566285 hasConcept C55493867 @default.
• W2167566285 hasConcept C64927066 @default.
• W2167566285 hasConcept C71240020 @default.
• W2167566285 hasConcept C8010536 @default.
• W2167566285 hasConcept C84772758 @default.
• W2167566285 hasConceptScore W2167566285C104317684 @default.
• W2167566285 hasConceptScore W2167566285C145148216 @default.
• W2167566285 hasConceptScore W2167566285C173681060 @default.
• W2167566285 hasConceptScore W2167566285C178790620 @default.
• W2167566285 hasConceptScore W2167566285C181199279 @default.
• W2167566285 hasConceptScore W2167566285C185592680 @default.
• W2167566285 hasConceptScore W2167566285C189754071 @default.
• W2167566285 hasConceptScore W2167566285C23265538 @default.
• W2167566285 hasConceptScore W2167566285C40325409 @default.
• W2167566285 hasConceptScore W2167566285C55493867 @default.
• W2167566285 hasConceptScore W2167566285C64927066 @default.
• W2167566285 hasConceptScore W2167566285C71240020 @default.
• W2167566285 hasConceptScore W2167566285C8010536 @default.
• W2167566285 hasConceptScore W2167566285C84772758 @default.
• W2167566285 hasLocation W21675662851 @default.
• W2167566285 hasLocation W21675662852 @default.
• W2167566285 hasLocation W21675662853 @default.
• W2167566285 hasOpenAccess W2167566285 @default.
• W2167566285 hasPrimaryLocation W21675662851 @default.
• W2167566285 hasRelatedWork W1971941442 @default.
• W2167566285 hasRelatedWork W1984984347 @default.
• W2167566285 hasRelatedWork W2012855365 @default.
• W2167566285 hasRelatedWork W2025477516 @default.
• W2167566285 hasRelatedWork W2051839246 @default.
• W2167566285 hasRelatedWork W2089077408 @default.
• W2167566285 hasRelatedWork W2113883513 @default.
• W2167566285 hasRelatedWork W2167566285 @default.
• W2167566285 hasRelatedWork W4232582927 @default.
• W2167566285 hasRelatedWork W8846158 @default.
• W2167566285 hasVolume "1567" @default.
• W2167566285 isParatext "false" @default.

• next