FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167644757> ?p ?o ?g. }

• W2167644757 endingPage "156" @default.
• W2167644757 startingPage "145" @default.
• W2167644757 abstract "Several theories have been advanced to explain the elevation in urinary PCO2 during bicarbonate loading and include: (a) H+ secretion, (b) countercurrent system for CO2, (c) the ampholyte properties of bicarbonate, and (d) mixing of urine of disparate bicarbonate and butter concentrations. In this study microelectrodes were used to measure in situ and equilibrium pH (pHis and pHeq) and PCO2 in control and bicarbonate loaded rats before and after infusion of carbonic anhydrase. The disequilibrium pH method (pHdq = pHis - pHeq) was used to demonstrate H+ secretion. Control rats excreting an acid urine (pH = 6.04 +/- 0.06) failed to display a significant disequilibrium pH at the base (BCD), or tip (TCD) of the papillary collecting duct. Urine pH (7.54 +/- 0.12), and urine to blood (U-B) PCO2 increased significantly during NaHCO3 loading while PCO2 at the BCD and TCD also increased (95 +/- 4 and 122 +/- 4). Furthermore, an acid disequilibrium pH was present at both the BCD and TCD (-0.42 +/- 0.04 and -0.36 +/- 0.03) and was obliterated by carbonic anhydrase. Comparison of the PCO2 in the BCD or TCD with the adjacent vasa recta revealed similar values (r = 0.97). It is concluded that H+ secretion by the collecting duct into bicarbonate containing fluid with delayed dehydration of H2CO3, is the most likely determinant of the U-B PCO2 in alkaline urine. Similar values for PCO2 in the collecting duct and the adjacent vasa recta suggests trapping of CO2 in the medullary countercurrent system. The rise in PCO2 occurs both along the collecting duct and after exit from the papilla." @default.
• W2167644757 created "2016-06-24" @default.
• W2167644757 creator A5043231729 @default.
• W2167644757 date "1982-01-01" @default.
• W2167644757 modified "2023-10-16" @default.
• W2167644757 title "Hydrogen ion secretion by the collecting duct as a determinant of the urine to blood PCO2 gradient in alkaline urine." @default.
• W2167644757 cites W185618015 @default.
• W2167644757 cites W1973697188 @default.
• W2167644757 cites W1978710590 @default.
• W2167644757 cites W1980557040 @default.
• W2167644757 cites W1997887373 @default.
• W2167644757 cites W2000410542 @default.
• W2167644757 cites W2000717752 @default.
• W2167644757 cites W2002952500 @default.
• W2167644757 cites W2029345937 @default.
• W2167644757 cites W2054885135 @default.
• W2167644757 cites W2071325348 @default.
• W2167644757 cites W2099203166 @default.
• W2167644757 cites W2126521384 @default.
• W2167644757 cites W2235449736 @default.
• W2167644757 cites W2258125718 @default.
• W2167644757 cites W2395996068 @default.
• W2167644757 cites W2399212464 @default.
• W2167644757 cites W2417411929 @default.
• W2167644757 cites W2419439542 @default.
• W2167644757 cites W2431341975 @default.
• W2167644757 cites W2461137910 @default.
• W2167644757 cites W2464380748 @default.
• W2167644757 cites W2470226895 @default.
• W2167644757 cites W2470879496 @default.
• W2167644757 doi "https://doi.org/10.1172/jci110425" @default.
• W2167644757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/371178" @default.
• W2167644757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6274913" @default.
• W2167644757 hasPublicationYear "1982" @default.
• W2167644757 type Work @default.
• W2167644757 sameAs 2167644757 @default.
• W2167644757 citedByCount "86" @default.
• W2167644757 countsByYear W21676447572012 @default.
• W2167644757 countsByYear W21676447572013 @default.
• W2167644757 countsByYear W21676447572014 @default.
• W2167644757 countsByYear W21676447572015 @default.
• W2167644757 countsByYear W21676447572016 @default.
• W2167644757 countsByYear W21676447572017 @default.
• W2167644757 countsByYear W21676447572018 @default.
• W2167644757 countsByYear W21676447572019 @default.
• W2167644757 countsByYear W21676447572021 @default.
• W2167644757 countsByYear W21676447572022 @default.
• W2167644757 crossrefType "journal-article" @default.
• W2167644757 hasAuthorship W2167644757A5043231729 @default.
• W2167644757 hasBestOaLocation W21676447571 @default.
• W2167644757 hasConcept C126322002 @default.
• W2167644757 hasConcept C134018914 @default.
• W2167644757 hasConcept C147789679 @default.
• W2167644757 hasConcept C158171629 @default.
• W2167644757 hasConcept C178790620 @default.
• W2167644757 hasConcept C181199279 @default.
• W2167644757 hasConcept C185592680 @default.
• W2167644757 hasConcept C2775914622 @default.
• W2167644757 hasConcept C2777140959 @default.
• W2167644757 hasConcept C2777858879 @default.
• W2167644757 hasConcept C2778437025 @default.
• W2167644757 hasConcept C2779608910 @default.
• W2167644757 hasConcept C2780026642 @default.
• W2167644757 hasConcept C2780091579 @default.
• W2167644757 hasConcept C2781112554 @default.
• W2167644757 hasConcept C43617362 @default.
• W2167644757 hasConcept C537181965 @default.
• W2167644757 hasConcept C55493867 @default.
• W2167644757 hasConcept C56906281 @default.
• W2167644757 hasConcept C71924100 @default.
• W2167644757 hasConcept C86803240 @default.
• W2167644757 hasConceptScore W2167644757C126322002 @default.
• W2167644757 hasConceptScore W2167644757C134018914 @default.
• W2167644757 hasConceptScore W2167644757C147789679 @default.
• W2167644757 hasConceptScore W2167644757C158171629 @default.
• W2167644757 hasConceptScore W2167644757C178790620 @default.
• W2167644757 hasConceptScore W2167644757C181199279 @default.
• W2167644757 hasConceptScore W2167644757C185592680 @default.
• W2167644757 hasConceptScore W2167644757C2775914622 @default.
• W2167644757 hasConceptScore W2167644757C2777140959 @default.
• W2167644757 hasConceptScore W2167644757C2777858879 @default.
• W2167644757 hasConceptScore W2167644757C2778437025 @default.
• W2167644757 hasConceptScore W2167644757C2779608910 @default.
• W2167644757 hasConceptScore W2167644757C2780026642 @default.
• W2167644757 hasConceptScore W2167644757C2780091579 @default.
• W2167644757 hasConceptScore W2167644757C2781112554 @default.
• W2167644757 hasConceptScore W2167644757C43617362 @default.
• W2167644757 hasConceptScore W2167644757C537181965 @default.
• W2167644757 hasConceptScore W2167644757C55493867 @default.
• W2167644757 hasConceptScore W2167644757C56906281 @default.
• W2167644757 hasConceptScore W2167644757C71924100 @default.
• W2167644757 hasConceptScore W2167644757C86803240 @default.
• W2167644757 hasIssue "1" @default.
• W2167644757 hasLocation W21676447571 @default.
• W2167644757 hasLocation W21676447572 @default.
• W2167644757 hasLocation W21676447573 @default.
• W2167644757 hasLocation W21676447574 @default.
• W2167644757 hasOpenAccess W2167644757 @default.

• next