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- W2167654342 abstract "MYH-associated polyposis (MAP; sometimes referred to as MUTYH-associated polyposis) is a rare, autosomal recessive, inherited condition. It is clinically similar to familial adenomatous polyposis (FAP), characterised by the development of 10 to hundreds of colorectal adenomas, which usually develop during young adulthood. The development of these polyps lead to an increased lifetime risk of colorectal cancer. Once diagnosed, the treatment, surgical options, and ongoing surveillance of MAP is similar in nature to FAP. As with FAP, the diagnosis of MAP is based clinically on the identification of colorectal adenomas and may be confirmed by genetic testing. The main difference is the recessive inheritance pattern, which has an important effect on the care of the family. This article will review the natural history of MAP and discuss the recommended screening and surveillance of this patient group." @default.
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- W2167654342 date "2014-04-01" @default.
- W2167654342 modified "2023-10-18" @default.
- W2167654342 title "MYH-associated polyposis: natural history and care of the patient" @default.
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- W2167654342 doi "https://doi.org/10.12968/gasn.2014.12.3.20" @default.
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