Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167810040> ?p ?o ?g. }
- W2167810040 endingPage "e142" @default.
- W2167810040 startingPage "e135" @default.
- W2167810040 abstract "The present study compared the effects of adjuvant bevacizumab and 5-fluorouracil on the efficacy and safety of trabeculectomy.A nonrandomized, prospective, interventional case study.A total of 62 patients in two groups undergoing primary trabeculectomy.In Group 1 (21 primary open-angle glaucoma, nine pseudoexfoliative glaucoma), trabeculectomy was performed with an adjuvant 5% solution of 5-fluorouracil administered for 4 min, intraoperatively. In Group 2 (21 primary open-angle glaucoma, 11 pseudoexfoliative glaucoma), trabeculectomy was enhanced with 1.25 mg of bevacizumab applied subconjunctivally immediately before and after surgery and again 1 and 7 days after surgery.Intraocular pressure, best corrected visual acuity, visual field index, bleb morphology, cornel endothelial cell count.Mean intraocular pressure was 28.0 ± 8.0 mmHg before 5-fluorouracil-augmented trabeculectomy and 27.8 ± 9.5 mmHg before bevacizumab-augmented trabeculectomy. After 12 months, mean intraocular pressure was 13.6 ± 4.4 mmHg in the 5-fluorouracil group and 14.7 ± 4.7 mmHg in the bevacizumab group. A 30% reduction of initial intraocular pressure was attained in 86.7% of patients in the 5-fluorouracil group and 78.1% of patients in the bevacizumab group at the end of follow up. No significant differences were noted between the two studied groups with respect to corneal endothelial density, visual field indices and postoperative complications.The 12-month intraocular pressure results showed no significant differences between the two groups of patients after bevacizumab or 5-fluorouracil to augment trabeculectomy. However, to obtain successful intraocular pressure control more patients in bevacizumab group needed medical therapy." @default.
- W2167810040 created "2016-06-24" @default.
- W2167810040 creator A5024481415 @default.
- W2167810040 creator A5064885933 @default.
- W2167810040 creator A5083709011 @default.
- W2167810040 date "2012-05-01" @default.
- W2167810040 modified "2023-09-27" @default.
- W2167810040 title "Comparison of the use of 5-fluorouracil and bevacizumab in primary trabeculectomy: results at 1 year" @default.
- W2167810040 cites W123239899 @default.
- W2167810040 cites W1573821968 @default.
- W2167810040 cites W158364456 @default.
- W2167810040 cites W180387481 @default.
- W2167810040 cites W1976490710 @default.
- W2167810040 cites W1978225963 @default.
- W2167810040 cites W1987087672 @default.
- W2167810040 cites W1987644022 @default.
- W2167810040 cites W1990180695 @default.
- W2167810040 cites W1991286734 @default.
- W2167810040 cites W1994961832 @default.
- W2167810040 cites W2006432488 @default.
- W2167810040 cites W2011003854 @default.
- W2167810040 cites W2021022810 @default.
- W2167810040 cites W2027942320 @default.
- W2167810040 cites W2028256742 @default.
- W2167810040 cites W2031501852 @default.
- W2167810040 cites W2033245558 @default.
- W2167810040 cites W2045247659 @default.
- W2167810040 cites W2048210828 @default.
- W2167810040 cites W2048276040 @default.
- W2167810040 cites W2055965573 @default.
- W2167810040 cites W2068346978 @default.
- W2167810040 cites W2074238578 @default.
- W2167810040 cites W2077022482 @default.
- W2167810040 cites W2082564771 @default.
- W2167810040 cites W2083794851 @default.
- W2167810040 cites W2093028623 @default.
- W2167810040 cites W2094433192 @default.
- W2167810040 cites W2122595579 @default.
- W2167810040 cites W2154459059 @default.
- W2167810040 cites W2161198160 @default.
- W2167810040 cites W2169077820 @default.
- W2167810040 cites W4245635197 @default.
- W2167810040 cites W52610832 @default.
- W2167810040 cites W68981680 @default.
- W2167810040 doi "https://doi.org/10.1111/j.1442-9071.2011.02608.x" @default.
- W2167810040 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21668792" @default.
- W2167810040 hasPublicationYear "2012" @default.
- W2167810040 type Work @default.
- W2167810040 sameAs 2167810040 @default.
- W2167810040 citedByCount "34" @default.
- W2167810040 countsByYear W21678100402012 @default.
- W2167810040 countsByYear W21678100402013 @default.
- W2167810040 countsByYear W21678100402014 @default.
- W2167810040 countsByYear W21678100402015 @default.
- W2167810040 countsByYear W21678100402016 @default.
- W2167810040 countsByYear W21678100402017 @default.
- W2167810040 countsByYear W21678100402018 @default.
- W2167810040 countsByYear W21678100402019 @default.
- W2167810040 countsByYear W21678100402021 @default.
- W2167810040 countsByYear W21678100402022 @default.
- W2167810040 countsByYear W21678100402023 @default.
- W2167810040 crossrefType "journal-article" @default.
- W2167810040 hasAuthorship W2167810040A5024481415 @default.
- W2167810040 hasAuthorship W2167810040A5064885933 @default.
- W2167810040 hasAuthorship W2167810040A5083709011 @default.
- W2167810040 hasBestOaLocation W21678100401 @default.
- W2167810040 hasConcept C118487528 @default.
- W2167810040 hasConcept C141071460 @default.
- W2167810040 hasConcept C2776694085 @default.
- W2167810040 hasConcept C2777802072 @default.
- W2167810040 hasConcept C2777824320 @default.
- W2167810040 hasConcept C2778257484 @default.
- W2167810040 hasConcept C2778527774 @default.
- W2167810040 hasConcept C2780456651 @default.
- W2167810040 hasConcept C2781092963 @default.
- W2167810040 hasConcept C71924100 @default.
- W2167810040 hasConceptScore W2167810040C118487528 @default.
- W2167810040 hasConceptScore W2167810040C141071460 @default.
- W2167810040 hasConceptScore W2167810040C2776694085 @default.
- W2167810040 hasConceptScore W2167810040C2777802072 @default.
- W2167810040 hasConceptScore W2167810040C2777824320 @default.
- W2167810040 hasConceptScore W2167810040C2778257484 @default.
- W2167810040 hasConceptScore W2167810040C2778527774 @default.
- W2167810040 hasConceptScore W2167810040C2780456651 @default.
- W2167810040 hasConceptScore W2167810040C2781092963 @default.
- W2167810040 hasConceptScore W2167810040C71924100 @default.
- W2167810040 hasIssue "4" @default.
- W2167810040 hasLocation W21678100401 @default.
- W2167810040 hasLocation W21678100402 @default.
- W2167810040 hasOpenAccess W2167810040 @default.
- W2167810040 hasPrimaryLocation W21678100401 @default.
- W2167810040 hasRelatedWork W1583896408 @default.
- W2167810040 hasRelatedWork W1968574077 @default.
- W2167810040 hasRelatedWork W1988712767 @default.
- W2167810040 hasRelatedWork W2022049485 @default.
- W2167810040 hasRelatedWork W2070809705 @default.
- W2167810040 hasRelatedWork W2118707548 @default.
- W2167810040 hasRelatedWork W2167810040 @default.