FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167821666> ?p ?o ?g. }

• W2167821666 endingPage "422" @default.
• W2167821666 startingPage "415" @default.
• W2167821666 abstract "Isoliquiritigenin (ISL), a chalcone and liquiritigenin (LTG), a flavonoid found in licorice roots and several other plants. ISL displays antioxidant, anti-inflammatory, antitumor and hepatoprotective activities whereas LTG is an estrogenic compound, acts as an agonist selective for the β-subtype of the oestrogen receptor. Both the phenolics were isolated from the rhizomes of Glycyrrhiza glabra. Five derivatives from ISL and four derivatives from LTG were synthesized. All the compounds were established by extensive spectroscopic analyses and screened through oral glucose tolerance test to gain preliminary information regarding the antihyperglycemic effect in normal Swiss albino male mice. ISL (1), ISL derivatives 3, 4, 5, 7 and LTG derivatives 9 and 10 showed significant blood glucose lowering effect. The structure-activity relationship indicated that the presence of ether and ester groups in ISL and LTG analogues are important for exhibiting the activity. Compounds 1, 4 and 10 were selected for in vivo antidiabetic activity and found to be potential candidates for treatment of diabetes. It is the first report on antidiabetic activity of ISL derivative 4 and LTG derivative 10." @default.
• W2167821666 created "2016-06-24" @default.
• W2167821666 creator A5047782678 @default.
• W2167821666 creator A5073892933 @default.
• W2167821666 creator A5078869149 @default.
• W2167821666 creator A5078906878 @default.
• W2167821666 creator A5079704157 @default.
• W2167821666 date "2014-03-01" @default.
• W2167821666 modified "2023-10-02" @default.
• W2167821666 title "In vivo anti-diabetic activity of derivatives of isoliquiritigenin and liquiritigenin" @default.
• W2167821666 cites W1993528208 @default.
• W2167821666 cites W1995413374 @default.
• W2167821666 cites W2002281820 @default.
• W2167821666 cites W2004969093 @default.
• W2167821666 cites W2009418014 @default.
• W2167821666 cites W2014226983 @default.
• W2167821666 cites W2016185211 @default.
• W2167821666 cites W2034788356 @default.
• W2167821666 cites W2036501990 @default.
• W2167821666 cites W2038613550 @default.
• W2167821666 cites W2040392353 @default.
• W2167821666 cites W2047134127 @default.
• W2167821666 cites W2049381328 @default.
• W2167821666 cites W2055011154 @default.
• W2167821666 cites W2057698030 @default.
• W2167821666 cites W2073765627 @default.
• W2167821666 cites W2079501949 @default.
• W2167821666 cites W2102196935 @default.
• W2167821666 cites W2140818406 @default.
• W2167821666 cites W2145953489 @default.
• W2167821666 cites W2146081152 @default.
• W2167821666 cites W2170479969 @default.
• W2167821666 cites W2175256660 @default.
• W2167821666 cites W2402067164 @default.
• W2167821666 cites W4232138652 @default.
• W2167821666 cites W4250065411 @default.
• W2167821666 doi "https://doi.org/10.1016/j.phymed.2013.10.015" @default.
• W2167821666 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24262065" @default.
• W2167821666 hasPublicationYear "2014" @default.
• W2167821666 type Work @default.
• W2167821666 sameAs 2167821666 @default.
• W2167821666 citedByCount "101" @default.
• W2167821666 countsByYear W21678216662014 @default.
• W2167821666 countsByYear W21678216662015 @default.
• W2167821666 countsByYear W21678216662016 @default.
• W2167821666 countsByYear W21678216662017 @default.
• W2167821666 countsByYear W21678216662018 @default.
• W2167821666 countsByYear W21678216662019 @default.
• W2167821666 countsByYear W21678216662020 @default.
• W2167821666 countsByYear W21678216662021 @default.
• W2167821666 countsByYear W21678216662022 @default.
• W2167821666 countsByYear W21678216662023 @default.
• W2167821666 crossrefType "journal-article" @default.
• W2167821666 hasAuthorship W2167821666A5047782678 @default.
• W2167821666 hasAuthorship W2167821666A5073892933 @default.
• W2167821666 hasAuthorship W2167821666A5078869149 @default.
• W2167821666 hasAuthorship W2167821666A5078906878 @default.
• W2167821666 hasAuthorship W2167821666A5079704157 @default.
• W2167821666 hasConcept C142724271 @default.
• W2167821666 hasConcept C150903083 @default.
• W2167821666 hasConcept C185592680 @default.
• W2167821666 hasConcept C204787440 @default.
• W2167821666 hasConcept C207001950 @default.
• W2167821666 hasConcept C2776974645 @default.
• W2167821666 hasConcept C2778004101 @default.
• W2167821666 hasConcept C2778521916 @default.
• W2167821666 hasConcept C2778609962 @default.
• W2167821666 hasConcept C2778958039 @default.
• W2167821666 hasConcept C2778993495 @default.
• W2167821666 hasConcept C2779054382 @default.
• W2167821666 hasConcept C2780764945 @default.
• W2167821666 hasConcept C55493867 @default.
• W2167821666 hasConcept C556039675 @default.
• W2167821666 hasConcept C71240020 @default.
• W2167821666 hasConcept C71924100 @default.
• W2167821666 hasConcept C86803240 @default.
• W2167821666 hasConcept C98274493 @default.
• W2167821666 hasConceptScore W2167821666C142724271 @default.
• W2167821666 hasConceptScore W2167821666C150903083 @default.
• W2167821666 hasConceptScore W2167821666C185592680 @default.
• W2167821666 hasConceptScore W2167821666C204787440 @default.
• W2167821666 hasConceptScore W2167821666C207001950 @default.
• W2167821666 hasConceptScore W2167821666C2776974645 @default.
• W2167821666 hasConceptScore W2167821666C2778004101 @default.
• W2167821666 hasConceptScore W2167821666C2778521916 @default.
• W2167821666 hasConceptScore W2167821666C2778609962 @default.
• W2167821666 hasConceptScore W2167821666C2778958039 @default.
• W2167821666 hasConceptScore W2167821666C2778993495 @default.
• W2167821666 hasConceptScore W2167821666C2779054382 @default.
• W2167821666 hasConceptScore W2167821666C2780764945 @default.
• W2167821666 hasConceptScore W2167821666C55493867 @default.
• W2167821666 hasConceptScore W2167821666C556039675 @default.
• W2167821666 hasConceptScore W2167821666C71240020 @default.
• W2167821666 hasConceptScore W2167821666C71924100 @default.
• W2167821666 hasConceptScore W2167821666C86803240 @default.
• W2167821666 hasConceptScore W2167821666C98274493 @default.
• W2167821666 hasIssue "4" @default.
• W2167821666 hasLocation W21678216661 @default.

• next