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- W2167841298 abstract "General synthetic methods for the grafting of peptide chains onto polyoxometalate clusters by the use of general activated precursors have been developed. Using a solution-phase approach, pre-synthesized peptides can be grafted to a metal oxide cluster to produce hybrids of unprecedented scale (up to 30 residues). An adapted solid-phase method allows the incorporation of these clusters, which may be regarded as novel hybrid unnatural amino acids, during the peptide synthesis itself. These methods may open the way for the automated synthesis of peptides and perhaps even proteins that contain “inorganic” amino acids." @default.
- W2167841298 created "2016-06-24" @default.
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- W2167841298 date "2014-03-12" @default.
- W2167841298 modified "2023-10-18" @default.
- W2167841298 title "Polyoxometalate Clusters Integrated into Peptide Chains and as Inorganic Amino Acids: Solution- and Solid-Phase Approaches" @default.
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- W2167841298 doi "https://doi.org/10.1002/anie.201311135" @default.
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