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- W2167884992 endingPage "142" @default.
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- W2167884992 abstract "Phosphodiesterases (PDEs) are important modulators of inflammation and wound healing. In this capacity, specific targeting of PDEs for the treatment of many diseases, including chronic obstructive pulmonary disease (COPD), has been investigated. Currently, treatment of COPD is suboptimal. PDE4 modulates the inflammatory response of the lung, and inhibition of PDE4 may be a novel, COPD-specific approach toward more effective treatment strategies. This review describes the state of PDE4-inhibitor therapy for use in COPD treatment. Clinical Pharmacology & Therapeutics (2012); 91 1, 134–142. doi:10.1038/clpt.2011.266" @default.
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- W2167884992 date "2011-11-30" @default.
- W2167884992 modified "2023-09-27" @default.
- W2167884992 title "PDE4: A Novel Target in the Treatment of Chronic Obstructive Pulmonary Disease" @default.
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- W2167884992 doi "https://doi.org/10.1038/clpt.2011.266" @default.
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