FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167907711> ?p ?o ?g. }

• W2167907711 endingPage "573" @default.
• W2167907711 startingPage "569" @default.
• W2167907711 abstract "Abstract Background The relationship between bullous pemphigoid ( BP ) and neurological disease has been the subject of numerous recent studies and BP antigens and their isoforms have been identified in the central nervous system ( CNS ). Whilst epidemiological data support this association, little is known about the pathomechanism behind this link and the immunological characteristics of patients with BP and neurological disease, other than multiple sclerosis ( MS ), has not been studied. Objective We aimed to compare the cutaneous immune response in BP patients with and without neurological disease, to investigate whether or not there is a distinctive immunopathological profile in patients with concomitant BP and neurological disease. Methods Seventy‐two patients with BP were included and divided into two groups; those with neurological disease ( BP + N , n = 43) and those without ( BP − N , n = 29). Patients in BP + N group had a confirmed neurological disease by a hospital physician, neurologist or psychiatrist with positive neurological imaging where appropriate, or a K arnofsky score of 50 or less due to mental impairment. All sera were analysed with indirect immunofluorescence ( IIF ) using serial dilutions up to 1:120000, immunoblotting ( IB ) and E nzyme‐linked immunosorbent assay ( ELISA ) for BP 180 and BP 230. Results Median antibody titres by IIF were 1:1600 vs. 1:800 for BP − N and BP + N , respectively, although the difference did not reach statistic significance ( P = 0.93, M ann– W hitney U ‐test). ELISA values for both BP 180 and BP 230 did not differ significantly between the two groups. Similarly, autoantibodies to specific antigens as identified by ELISA and IB were not related to the presence of neurological disease. Conclusion The results of this study indicate that patients with BP and neurological disease exhibit an immune response to both BP 180 and BP 230, thus the link between the CNS and the skin is not dependent on a specific antigen, but possibly both antigens or their isoforms may be exposed following a neurological insult, and play a role in generation of an immune response." @default.
• W2167907711 created "2016-06-24" @default.
• W2167907711 creator A5007962977 @default.
• W2167907711 creator A5009926815 @default.
• W2167907711 creator A5033907428 @default.
• W2167907711 creator A5071151868 @default.
• W2167907711 creator A5080537232 @default.
• W2167907711 creator A5083529701 @default.
• W2167907711 date "2013-03-26" @default.
• W2167907711 modified "2023-10-03" @default.
• W2167907711 title "Immunopathological characteristics of patients with bullous pemphigoid and neurological disease" @default.
• W2167907711 cites W1806907698 @default.
• W2167907711 cites W1984365144 @default.
• W2167907711 cites W2003728614 @default.
• W2167907711 cites W2010974498 @default.
• W2167907711 cites W2027242405 @default.
• W2167907711 cites W2044326268 @default.
• W2167907711 cites W2054438253 @default.
• W2167907711 cites W2062367869 @default.
• W2167907711 cites W2064406292 @default.
• W2167907711 cites W2084143268 @default.
• W2167907711 cites W2095454957 @default.
• W2167907711 cites W2101108802 @default.
• W2167907711 cites W2111752737 @default.
• W2167907711 cites W2113411541 @default.
• W2167907711 cites W2161481536 @default.
• W2167907711 cites W2164385416 @default.
• W2167907711 cites W2187935508 @default.
• W2167907711 cites W2338193938 @default.
• W2167907711 doi "https://doi.org/10.1111/jdv.12136" @default.
• W2167907711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23530989" @default.
• W2167907711 hasPublicationYear "2013" @default.
• W2167907711 type Work @default.
• W2167907711 sameAs 2167907711 @default.
• W2167907711 citedByCount "25" @default.
• W2167907711 countsByYear W21679077112013 @default.
• W2167907711 countsByYear W21679077112014 @default.
• W2167907711 countsByYear W21679077112015 @default.
• W2167907711 countsByYear W21679077112016 @default.
• W2167907711 countsByYear W21679077112017 @default.
• W2167907711 countsByYear W21679077112018 @default.
• W2167907711 countsByYear W21679077112019 @default.
• W2167907711 countsByYear W21679077112020 @default.
• W2167907711 countsByYear W21679077112021 @default.
• W2167907711 countsByYear W21679077112022 @default.
• W2167907711 crossrefType "journal-article" @default.
• W2167907711 hasAuthorship W2167907711A5007962977 @default.
• W2167907711 hasAuthorship W2167907711A5009926815 @default.
• W2167907711 hasAuthorship W2167907711A5033907428 @default.
• W2167907711 hasAuthorship W2167907711A5071151868 @default.
• W2167907711 hasAuthorship W2167907711A5080537232 @default.
• W2167907711 hasAuthorship W2167907711A5083529701 @default.
• W2167907711 hasConcept C101180180 @default.
• W2167907711 hasConcept C118552586 @default.
• W2167907711 hasConcept C126322002 @default.
• W2167907711 hasConcept C159654299 @default.
• W2167907711 hasConcept C163764329 @default.
• W2167907711 hasConcept C16568411 @default.
• W2167907711 hasConcept C203014093 @default.
• W2167907711 hasConcept C2778075117 @default.
• W2167907711 hasConcept C2779134260 @default.
• W2167907711 hasConcept C2779252107 @default.
• W2167907711 hasConcept C2780640218 @default.
• W2167907711 hasConcept C71924100 @default.
• W2167907711 hasConcept C90924648 @default.
• W2167907711 hasConceptScore W2167907711C101180180 @default.
• W2167907711 hasConceptScore W2167907711C118552586 @default.
• W2167907711 hasConceptScore W2167907711C126322002 @default.
• W2167907711 hasConceptScore W2167907711C159654299 @default.
• W2167907711 hasConceptScore W2167907711C163764329 @default.
• W2167907711 hasConceptScore W2167907711C16568411 @default.
• W2167907711 hasConceptScore W2167907711C203014093 @default.
• W2167907711 hasConceptScore W2167907711C2778075117 @default.
• W2167907711 hasConceptScore W2167907711C2779134260 @default.
• W2167907711 hasConceptScore W2167907711C2779252107 @default.
• W2167907711 hasConceptScore W2167907711C2780640218 @default.
• W2167907711 hasConceptScore W2167907711C71924100 @default.
• W2167907711 hasConceptScore W2167907711C90924648 @default.
• W2167907711 hasFunder F4320320080 @default.
• W2167907711 hasIssue "5" @default.
• W2167907711 hasLocation W21679077111 @default.
• W2167907711 hasLocation W21679077112 @default.
• W2167907711 hasOpenAccess W2167907711 @default.
• W2167907711 hasPrimaryLocation W21679077111 @default.
• W2167907711 hasRelatedWork W1573608824 @default.
• W2167907711 hasRelatedWork W1797937449 @default.
• W2167907711 hasRelatedWork W1942654056 @default.
• W2167907711 hasRelatedWork W1986217778 @default.
• W2167907711 hasRelatedWork W2184265427 @default.
• W2167907711 hasRelatedWork W2516066266 @default.
• W2167907711 hasRelatedWork W2734434717 @default.
• W2167907711 hasRelatedWork W3046802463 @default.
• W2167907711 hasRelatedWork W2183638311 @default.
• W2167907711 hasRelatedWork W3031994139 @default.
• W2167907711 hasVolume "28" @default.
• W2167907711 isParatext "false" @default.
• W2167907711 isRetracted "false" @default.
• W2167907711 magId "2167907711" @default.

• next