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- W2167919958 abstract "ABSTRACT Mutant proteins with eight amino acid deletions in putative surface loops 2 and 3 of the imipenem-specific porin OprD of Pseudomonas aeruginosa failed to reconstitute imipenem susceptibility in an oprD -deficient background. The loop 3 deletion prevented the ability of imipenem to inhibit KCl conductance through the OprD channel, as previously shown for a loop 2 deletion. This suggests that both loops 2 and 3 have a role in imipenem binding to the OprD channel." @default.
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- W2167919958 date "2000-07-01" @default.
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- W2167919958 title "Role of Putative Loops 2 and 3 in Imipenem Passage through the Specific Porin OprD of <i>Pseudomonas aeruginosa</i>" @default.
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- W2167919958 doi "https://doi.org/10.1128/aac.44.7.1983-1985.2000" @default.
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