Matches in SemOpenAlex for { <https://semopenalex.org/work/W2167954691> ?p ?o ?g. }
- W2167954691 endingPage "250" @default.
- W2167954691 startingPage "241" @default.
- W2167954691 abstract "ABSTRACT We have identified in the fission yeast Schizosaccharomyces pombe a MutS homolog that shows highest homology to the Msh2 subgroup. msh2 disruption gives rise to increased mitotic mutation rates and increased levels of postmeiotic segregation of genetic markers. In bandshift assays performed with msh2 Δ cell extracts, a general mismatch-binding activity is absent. By complementation assays, we showed that S. pombe msh2 is allelic with the previously identified swi8 and mut3 genes, which are involved in mating-type switching. The swi8-137 mutant has a mutation in the msh2 gene which causes a truncated Msh2 peptide lacking a putative DNA-binding domain. Cytological analysis revealed that during meiotic prophase of msh2 -defective cells, chromosomal structures were frequently formed; such structures are rarely found in the wild type. Our data show that besides having a function in mismatch repair, S. pombe msh2 is required for correct termination of copy synthesis during mating-type switching as well as for proper organization of chromosomes during meiosis." @default.
- W2167954691 created "2016-06-24" @default.
- W2167954691 creator A5000828582 @default.
- W2167954691 creator A5003660281 @default.
- W2167954691 creator A5004075116 @default.
- W2167954691 creator A5009318905 @default.
- W2167954691 creator A5022253764 @default.
- W2167954691 creator A5064480145 @default.
- W2167954691 creator A5084053908 @default.
- W2167954691 creator A5084302384 @default.
- W2167954691 creator A5089080821 @default.
- W2167954691 date "1999-01-01" @default.
- W2167954691 modified "2023-10-14" @default.
- W2167954691 title "The <i>msh2</i> Gene of <i>Schizosaccharomyces pombe</i> Is Involved in Mismatch Repair, Mating-Type Switching, and Meiotic Chromosome Organization" @default.
- W2167954691 cites W1491342176 @default.
- W2167954691 cites W1533214975 @default.
- W2167954691 cites W1546766865 @default.
- W2167954691 cites W1572269097 @default.
- W2167954691 cites W161746494 @default.
- W2167954691 cites W1833842636 @default.
- W2167954691 cites W1862994794 @default.
- W2167954691 cites W1900430859 @default.
- W2167954691 cites W1925842451 @default.
- W2167954691 cites W1965204294 @default.
- W2167954691 cites W1967205646 @default.
- W2167954691 cites W1967707926 @default.
- W2167954691 cites W1973782344 @default.
- W2167954691 cites W1982036729 @default.
- W2167954691 cites W1983385891 @default.
- W2167954691 cites W1987847307 @default.
- W2167954691 cites W1996323131 @default.
- W2167954691 cites W2006471304 @default.
- W2167954691 cites W2011719683 @default.
- W2167954691 cites W2013296976 @default.
- W2167954691 cites W2013735712 @default.
- W2167954691 cites W2014571977 @default.
- W2167954691 cites W2015532523 @default.
- W2167954691 cites W2016544300 @default.
- W2167954691 cites W2029579644 @default.
- W2167954691 cites W2034188127 @default.
- W2167954691 cites W2035416711 @default.
- W2167954691 cites W2037906550 @default.
- W2167954691 cites W2038950750 @default.
- W2167954691 cites W2049874412 @default.
- W2167954691 cites W2055993339 @default.
- W2167954691 cites W2059833158 @default.
- W2167954691 cites W2064879624 @default.
- W2167954691 cites W2068480338 @default.
- W2167954691 cites W2071225439 @default.
- W2167954691 cites W2075240053 @default.
- W2167954691 cites W2075637141 @default.
- W2167954691 cites W2075810299 @default.
- W2167954691 cites W2081970237 @default.
- W2167954691 cites W2082311854 @default.
- W2167954691 cites W2089509232 @default.
- W2167954691 cites W2094983671 @default.
- W2167954691 cites W2107866807 @default.
- W2167954691 cites W2108294716 @default.
- W2167954691 cites W2110627805 @default.
- W2167954691 cites W2110847368 @default.
- W2167954691 cites W2114968751 @default.
- W2167954691 cites W2118713976 @default.
- W2167954691 cites W2121079878 @default.
- W2167954691 cites W2127305172 @default.
- W2167954691 cites W2130369250 @default.
- W2167954691 cites W2133492775 @default.
- W2167954691 cites W2141798197 @default.
- W2167954691 cites W2152693329 @default.
- W2167954691 cites W2156941816 @default.
- W2167954691 cites W2167643094 @default.
- W2167954691 cites W2170472485 @default.
- W2167954691 cites W2202176365 @default.
- W2167954691 cites W2305649060 @default.
- W2167954691 cites W2490426826 @default.
- W2167954691 cites W2493670101 @default.
- W2167954691 cites W4232843783 @default.
- W2167954691 cites W4240539663 @default.
- W2167954691 cites W4247771351 @default.
- W2167954691 cites W4256374979 @default.
- W2167954691 doi "https://doi.org/10.1128/mcb.19.1.241" @default.
- W2167954691 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/83882" @default.
- W2167954691 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9858548" @default.
- W2167954691 hasPublicationYear "1999" @default.
- W2167954691 type Work @default.
- W2167954691 sameAs 2167954691 @default.
- W2167954691 citedByCount "48" @default.
- W2167954691 countsByYear W21679546912013 @default.
- W2167954691 countsByYear W21679546912014 @default.
- W2167954691 countsByYear W21679546912015 @default.
- W2167954691 countsByYear W21679546912016 @default.
- W2167954691 countsByYear W21679546912017 @default.
- W2167954691 countsByYear W21679546912018 @default.
- W2167954691 countsByYear W21679546912019 @default.
- W2167954691 countsByYear W21679546912020 @default.
- W2167954691 countsByYear W21679546912021 @default.
- W2167954691 countsByYear W21679546912023 @default.
- W2167954691 crossrefType "journal-article" @default.
- W2167954691 hasAuthorship W2167954691A5000828582 @default.