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- W2168049797 abstract "articleFormation and actions of leukotrienesP. J. PiperP. J. PiperPublished Online:01 Apr 1984https://doi.org/10.1152/physrev.1984.64.2.744MoreSectionsPDF (3 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInEmailWeChat Previous Back to Top Download PDF FiguresReferencesRelatedInformationCited ByAnti-anaphylactic action of nordihydroguaiaretic acid in antigen sensitized guinea pigsRespiratory Physiology & Neurobiology, Vol. 234Leukotriene modifiers in the treatment of cardiovascular diseases15 September 2008 | Journal of Leukocyte Biology, Vol. 84, No. 6Synthesis of the Leukotrienes20 February 2007Effects of a cysteinyl leukotriene receptor antagonist on eosinophil recruitment in experimental allergic rhinitisImmunology, Vol. 113, No. 2An update of the leukotriene modulators for the treatment of asthma24 February 2005 | Expert Opinion on Investigational Drugs, Vol. 13, No. 7Cysteinyl-leukotrienes and the liverProstaglandins & Other Lipid Mediators, Vol. 72, No. 1-2Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the ratAlan E. Jones, John A. Watts, Jacob P. Debelak, Lisa R. Thornton, John G. Younger, and Jeffrey A. Kline1 June 2003 | American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 284, No. 6Of Mice and MenAmerican Journal of Respiratory Cell and Molecular Biology, Vol. 28, No. 1Exercise in elite summer athletes: Challenges for diagnosisJournal of Allergy and Clinical Immunology, Vol. 110, No. 3The Role of Antileukotrienes in the Treatment of Asthma24 June 2016 | International Journal of Immunopathology and Pharmacology, Vol. 15, No. 3Cysteinyl leukotriene receptorsProstaglandins & Other Lipid Mediators, Vol. 68-69Characterization of the human cysteinyl leukotriene CysLT1 receptorNature, Vol. 399, No. 6738Leukotriene C4 from vascular endothelium enhances neutrophil adhesivenessProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 56, No. 2Role of Leukotriene B4 and Interleukin-8 in Acute Bacterial and Viral Otitis Media29 June 2016 | Annals of Otology, Rhinology & Laryngology, Vol. 105, No. 12Beneficial effects of combined thromboxane and leukotriene receptor antagonism in hemorrhagic shockCritical Care Medicine, Vol. 23, No. 2Haemodynamic and haematologic effects of Acanthaster planci venom in dogsToxicon, Vol. 32, No. 10The pharmacologic effects of 5-[3,5-BIS(1,1-dimethylethyl)-4-hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritationProstaglandins, Vol. 47, No. 1Nociception from skeletal muscle in relation to clinical muscle painPain, Vol. 54, No. 3Effect of 5-lipoxygenase and cyclooxygenase blockade on porcine hemodynamics during continous infusion of platelet-activating factorProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 49, No. 2Identification and target-size analysis of the leukotriene D4 receptor in the human THP-1 cell lineBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1177, No. 3Anti-leukotriene effects of WY-50,295 tromethamine in isolated guinea pig pulmonary tissuesEuropean Journal of Pharmacology, Vol. 234, No. 2-3From lung hypersensitivity to bronchial hyperreactivityBiochemical Pharmacology, Vol. 45, No. 4Characterization of the leukotriene D4 receptor in dimethylsulphoxide-differentiated U937 cells: comparison with the leukotriene D4 receptor in human lung and guinea-pig lungEuropean Journal of Pharmacology: Molecular Pharmacology, Vol. 244, No. 3Cloricromene inhibits leukotriene formation by human polymorphonuclear leucocytes by suppressing arachidonate release from membrane phospholipidsBiochemical Pharmacology, Vol. 45, No. 1Liver cytoprotection by prostaglandinsPharmacology & Therapeutics, Vol. 58, No. 1Effect of BI-L-239, A-64077 and MK-886 on leukotriene B4 synthesis by chopped guinea pig lung and on antigen-induced tracheal contractionProstaglandins, Vol. 44, No. 6Glutathione S-transferase-dependent conjugation of leukotriene a4-methyl ester to leukotriene C4-methyl ester in mammalian skinBiochemical Pharmacology, Vol. 44, No. 10SK&F 104353, a selective leukotriene receptor antagonist, inhibits leukotriene D4- and antigen-induced bronchoconstriction in cynomolgus monkeysPulmonary Pharmacology, Vol. 5, No. 3Early efficacy data with a newer generation of LTD4 antagonists in antiasthma trials: Early promise for a single mediator antagonistPulmonary Pharmacology, Vol. 5, No. 2Influence of leukotriene D4 on arterial pressure and gastrointestinal electrical activity in the conscious pigletProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 46, No. 1The discovery and development of zileuton: An orally active 5-lipoxygenase inhibitorInternational Journal of Immunopharmacology, Vol. 14, No. 3Time-dependent alterations of leukotriene production and catabolism in rat peritoneal macrophages following intraperitoneal injection of thioglycollate brothProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 45, No. 1Neurotensin elevates hematocrit and plasma levels of the leukotrienes, LTB4, LTC4, LTD4 and LTE4, in anesthetized ratsPeptides, Vol. 12, No. 5Effect of the LTD4 receptor antagonist LY203647 on endotoxic shock sequelae in the ratEuropean Journal of Pharmacology, Vol. 199, No. 2Characterization of the leukotriene D4 receptor in hyperreactive rat lungEuropean Journal of Pharmacology, Vol. 194, No. 1FLAP: a novel drug target for inhibiting the synthesis of leukotrienesTrends in Pharmacological Sciences, Vol. 12Inhibition of leukotriene B4 biosynthesis by disulfiram and A-64077 during carrageenan-induced pleurisy in the ratGeneral Pharmacology: The Vascular System, Vol. 22, No. 2Pharmacologic and pharmacokinetic profile of SK&F S-106203, a potent, orally active peptidoleukotriene receptor antagonist, in guinea-pigPulmonary Pharmacology, Vol. 4, No. 3Specific binding of 3H-ICI 198, 615, a potent LTD4 antagonist, to guinea pig cardiac ventricular membranesProstaglandins, Vol. 39, No. 3[64] Eicosanoid interactions between platelets, endothelial cells, and neutrophilsAntigen-dependent leukotriene synthesis and histamine release from IgG1 passively-sensitized guinea pig lungs ex vivo: Relationship between serum levels of antigen-specific IgG1 and mediator synthesis/releasePulmonary Pharmacology, Vol. 3, No. 4Metabolism of leukotriene D4 by rat peritoneal mast cellsProstaglandins, Vol. 38, No. 2Evaluation of immunity to feline infectious peritonitis in cats with cutaneous viral-induced delayed hypersensitivityVeterinary Immunology and Immunopathology, Vol. 21, No. 3-4Involvement of thromboxane and leukotriene in arachidonate induced coronary constriction in diabetic ratsDiabetologia, Vol. 32, No. 6Beneficial effects of a specific leukotriene receptor antagonist in splanchnic artery occlusion shockEuropean Journal of Pharmacology, Vol. 165, No. 2-3Amniotic fluid arachidonate lipoxygenase metabolites in preterm laborProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 36, No. 2Indomethacin and LY171883 modify porcine cardiopulmonary responses to leukotrienesProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 35, No. 3Amniotic fluid concentration of 5-hydroxyeicosatetraenoic acid is increased in human parturition at termProstaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), Vol. 35, No. 2Role of Leukotrienes in Inflammatory Bowel DiseaseThe pharmacology of antiglaucoma drugsPharmacology & Therapeutics, Vol. 43, No. 1Simple procedure for measuring the pharmacodynamics and analgesic potential of lipoxygenase inhibitorsJournal of Pharmacological Methods, Vol. 20, No. 4Preferential inhibition of 5-lipoxygenase activity by manoalideBiochemical Pharmacology, Vol. 37, No. 15Formation of cysteinyl-leukotrienes by human brain tissueBrain Research, Vol. 456, No. 2Adenosine and leukotrienes have a regulatory role in lung surfactant secretion in the newborn rabbitBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 960, No. 1Increased leukotriene B4 in bronchoalveolar lavage fluid and plasma of endotoxemic pigsProstaglandins, Leukotrienes and Essential Fatty Acids, Vol. 32, No. 2Autoradiographic localization of leukotriene C4 and D4 binding sites in guinea-pig lungProstaglandins, Vol. 35, No. 4Biochemical, physiological and clinical aspects of endotoxemiaMolecular Aspects of Medicine, Vol. 10, No. 6Further isolation of endogenous factors in canine and human plasma that inhibit [3H]norepinephrine accumulationNeurochemistry International, Vol. 12, No. 3Comparative studies on the leukotriene D4-metabolizing enzyme of different types of leukocytesComparative Biochemistry and Physiology Part B: Comparative Biochemistry, Vol. 89, No. 2Vascular smooth muscle cell leukotriene C4 synthesis: requirement for transcellular leukotriene A4 metabolismBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 922, No. 2Peptidoleukotrienes induce an endothelium-dependent relaxation of guiena pig main pulmonary artery and thoratic aortaProstaglandins, Vol. 34, No. 5Studies on the leukotriene D4-metabolizing enzyme of rat leukocytes, which catalyzes the conversion of leukotriene D4 to leukotriene E4Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 922, No. 1Hydroxyeicosatetraenoic acids are increased in bronchoalveolar lavage fluid of endotoxemic pigsProstaglandins, Vol. 34, No. 4Silent myocardial ischemia. I. Pathophysiology, frequency of occurrence, and approaches toward detectionAmerican Heart Journal, Vol. 114, No. 3Arachidonic acid metabolism by lipoxygenase pathways in intrauterine tissues of women at term of pregnancyProstaglandins, Leukotrienes and Medicine, Vol. 28, No. 3Conversion of leukotriene C 4 to leukotriene D 4 by a cell-surface enzyme of rat macrophagesBiochemical and Biophysical Research Communications, Vol. 147, No. 1Enterohepatic circulation of N-acetyl-leukotriene E4Prostaglandins, Vol. 34, No. 1The detection of 5-lipoxygenase and cyclo-oxygenase products in sputum of patients with chronic bronchitis and bronchiectasisProstaglandins, Vol. 33, No. 5Biliary and urinary excretion of peptide leukotrienes in the domestic pigProstaglandins, Vol. 33, No. 5The deleterious effect of FPL 55712 on gas exchange in the basenji-greyhound dog model of asthmaJournal of Critical Care, Vol. 2, No. 1Leukotriene C4 metabolism by hepatoma cells and liverAdvances in Enzyme Regulation, Vol. 26A simple and sensitive radioreceptor assay for leukotrienesProstaglandins, Vol. 33, No. 1Localization of leukotriene D4-metabolizing metalloenzyme on the cell surface of human neutrophilsBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 888, No. 3Verapamil depresses the synthesis of lipoxygenase products by hypoxic cardiac rat fibroblasts in cultureBiochemical Pharmacology, Vol. 35, No. 11The synthesis of N-acetyl-leukotriene E4 and its effects on cardiovascular and respiratory function of the anesthetized pigProstaglandins, Vol. 31, No. 6Leukotrienes stimulate phosphatidylcholine secretion in cultured type II pneumocytesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 876, No. 1Identification of the major endogenous leukotriene metabolite in the bile of rats as N-acetyl leukotrience E4Prostaglandins, Vol. 31, No. 2Release of leukotrienes into the perfusate of calcium-ionophore stimulated rabbit lungsBiochemical Pharmacology, Vol. 35, No. 2LTC4 ‘receptor’: its demonstration using airway and non-airway tissuesTrends in Pharmacological Sciences, Vol. 7Generation of lipoxygenase products in the avascular tissues of the eyeExperimental Eye Research, Vol. 41, No. 6On the inotropic effects of leukotrienes in the isolated urinary bladder of guinea pigs and ratsProstaglandins, Leukotrienes and Medicine, Vol. 20, No. 1New insights into the cellular mechanisms of vasospasThe American Journal of Cardiology, Vol. 56, No. 9Pulmonary microcirculatory responses to leukotrienes B4, C4 and D4 in sheepProstaglandins, Vol. 30, No. 3The use of drugs for the inhibition of prostaglandin or leukotriene synthesis from arachidonic acid is theoretically hazardousMedical Hypotheses, Vol. 17, No. 4The biosynthesis of leukotriene B4, the predominant lipoxygenase product in rabbit alveolar macrophages, is enhanced during immune activationBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 835, No. 1Arachidonic acid metabolites stimulate phosphatidylcholine secretion in primary cultures of type II pneumocytesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, Vol. 833, No. 2Inhibitors of lipoxygenase products improve survival in traumatic shockProstaglandins, Vol. 28, No. 4 More from this issue > Volume 64Issue 2April 1984Pages 744-761 Copyright & PermissionsCopyright © 1984 the American Physiological Societyhttps://doi.org/10.1152/physrev.1984.64.2.744PubMed6324254History Published online 1 April 1984 Published in print 1 April 1984 Metrics" @default.
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