FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168093722> ?p ?o ?g. }

• W2168093722 endingPage "1144" @default.
• W2168093722 startingPage "1135" @default.
• W2168093722 abstract "A series of copper(I) complexes of N,N′-disubstituted thioureas, [C6H5CONHCSNHR]Cu(I)Cl where R = C6H5 (1a), 2-ClC6H4 (2a), 3-ClC6H4 (3a), 4-ClC6H4 (4a), 2,3-Cl2C6H3 (5a), 2,4-Cl2C6H3 (6a), 2,5-Cl2C6H3 (7a), 2,6-Cl2C6H3 (8a), 3,4-Cl2C6H3 (9a) and 3,5-Cl2C6H3 (10a) have been synthesized. These complexes (1a–10a) have been characterized by elemental analyses, IR, 1H and 13C NMR spectroscopy, cyclic voltammetry and single crystal XRD for 1a and 8a, and for ligand 7. The X-ray crystal structures reveal that the complexes 1a and 8a are mononuclear in the solid state in which the copper atoms adopt a distorted tetrahedral geometry. In both the cases, the neutral N,N′-disubstituted thiourea ligands have been coordinated to the Cu(I) through the sulphur atom in a terminal mode. The complexes have been screened for their in vitro cytotoxic activity in human cell lines carcinomas A498 (Renal), EVSA-T (Breast), H226 (Lung), IGROV (Ovarian), M19 (Melanoma-Skin), MCF-7 (Breast) and WIDR (Colon). They show a moderate cytotoxicity against these seven human cancer cell lines comparable to that of the less active standard chemotherapeutic drugs used for comparison. They were also screened for their anti-bacterial activity and were found less active than the standard drug Imipenem." @default.
• W2168093722 created "2016-06-24" @default.
• W2168093722 creator A5015741348 @default.
• W2168093722 creator A5029952584 @default.
• W2168093722 creator A5037308345 @default.
• W2168093722 creator A5041284196 @default.
• W2168093722 creator A5049362443 @default.
• W2168093722 creator A5072850457 @default.
• W2168093722 creator A5090007108 @default.
• W2168093722 date "2009-08-01" @default.
• W2168093722 modified "2023-10-17" @default.
• W2168093722 title "Synthesis, structural characterization and in vitro cytotoxicity and anti-bacterial activity of some copper(I) complexes with N,N′-disubstituted thioureas" @default.
• W2168093722 cites W1503692911 @default.
• W2168093722 cites W1570613769 @default.
• W2168093722 cites W1579436444 @default.
• W2168093722 cites W1897085524 @default.
• W2168093722 cites W1969001566 @default.
• W2168093722 cites W1969635440 @default.
• W2168093722 cites W1974826646 @default.
• W2168093722 cites W1983467312 @default.
• W2168093722 cites W1988597887 @default.
• W2168093722 cites W1994707797 @default.
• W2168093722 cites W2022938402 @default.
• W2168093722 cites W2027338326 @default.
• W2168093722 cites W2030941620 @default.
• W2168093722 cites W2044303747 @default.
• W2168093722 cites W2046485777 @default.
• W2168093722 cites W2049516913 @default.
• W2168093722 cites W2054119278 @default.
• W2168093722 cites W2056769035 @default.
• W2168093722 cites W2061410259 @default.
• W2168093722 cites W2074978608 @default.
• W2168093722 cites W2078517732 @default.
• W2168093722 cites W2079741772 @default.
• W2168093722 cites W2080195619 @default.
• W2168093722 cites W2091706193 @default.
• W2168093722 cites W2102782361 @default.
• W2168093722 cites W2171592862 @default.
• W2168093722 cites W2479663229 @default.
• W2168093722 cites W288344440 @default.
• W2168093722 doi "https://doi.org/10.1016/j.jinorgbio.2009.05.014" @default.
• W2168093722 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19570580" @default.
• W2168093722 hasPublicationYear "2009" @default.
• W2168093722 type Work @default.
• W2168093722 sameAs 2168093722 @default.
• W2168093722 citedByCount "123" @default.
• W2168093722 countsByYear W21680937222012 @default.
• W2168093722 countsByYear W21680937222013 @default.
• W2168093722 countsByYear W21680937222014 @default.
• W2168093722 countsByYear W21680937222015 @default.
• W2168093722 countsByYear W21680937222016 @default.
• W2168093722 countsByYear W21680937222017 @default.
• W2168093722 countsByYear W21680937222018 @default.
• W2168093722 countsByYear W21680937222019 @default.
• W2168093722 countsByYear W21680937222020 @default.
• W2168093722 countsByYear W21680937222021 @default.
• W2168093722 countsByYear W21680937222022 @default.
• W2168093722 countsByYear W21680937222023 @default.
• W2168093722 crossrefType "journal-article" @default.
• W2168093722 hasAuthorship W2168093722A5015741348 @default.
• W2168093722 hasAuthorship W2168093722A5029952584 @default.
• W2168093722 hasAuthorship W2168093722A5037308345 @default.
• W2168093722 hasAuthorship W2168093722A5041284196 @default.
• W2168093722 hasAuthorship W2168093722A5049362443 @default.
• W2168093722 hasAuthorship W2168093722A5072850457 @default.
• W2168093722 hasAuthorship W2168093722A5090007108 @default.
• W2168093722 hasConcept C109316439 @default.
• W2168093722 hasConcept C115624301 @default.
• W2168093722 hasConcept C116569031 @default.
• W2168093722 hasConcept C127709339 @default.
• W2168093722 hasConcept C147789679 @default.
• W2168093722 hasConcept C170493617 @default.
• W2168093722 hasConcept C17525397 @default.
• W2168093722 hasConcept C178790620 @default.
• W2168093722 hasConcept C185592680 @default.
• W2168093722 hasConcept C202751555 @default.
• W2168093722 hasConcept C2777869211 @default.
• W2168093722 hasConcept C2780538656 @default.
• W2168093722 hasConcept C52859227 @default.
• W2168093722 hasConcept C544778455 @default.
• W2168093722 hasConcept C55493867 @default.
• W2168093722 hasConcept C71240020 @default.
• W2168093722 hasConcept C8010536 @default.
• W2168093722 hasConceptScore W2168093722C109316439 @default.
• W2168093722 hasConceptScore W2168093722C115624301 @default.
• W2168093722 hasConceptScore W2168093722C116569031 @default.
• W2168093722 hasConceptScore W2168093722C127709339 @default.
• W2168093722 hasConceptScore W2168093722C147789679 @default.
• W2168093722 hasConceptScore W2168093722C170493617 @default.
• W2168093722 hasConceptScore W2168093722C17525397 @default.
• W2168093722 hasConceptScore W2168093722C178790620 @default.
• W2168093722 hasConceptScore W2168093722C185592680 @default.
• W2168093722 hasConceptScore W2168093722C202751555 @default.
• W2168093722 hasConceptScore W2168093722C2777869211 @default.
• W2168093722 hasConceptScore W2168093722C2780538656 @default.
• W2168093722 hasConceptScore W2168093722C52859227 @default.
• W2168093722 hasConceptScore W2168093722C544778455 @default.
• W2168093722 hasConceptScore W2168093722C55493867 @default.

• next