FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168108114> ?p ?o ?g. }

• W2168108114 endingPage "587" @default.
• W2168108114 startingPage "581" @default.
• W2168108114 abstract "It is unclear how to effectively mitigate against irradiation injury. In this study, we studied the capacity of recombinant human insulin-like growth factor-I (rhIGF-I) on hematologic recovery in irradiated BALB/c mice and its possible mechanism. BALB/c mice were injected with rhIGF-I subcutaneously at a dose of 100 μg/kg twice daily for 7 days after total body irradiation. Compared with a saline control group, treatment with rhIGF-I significantly improved the survival of mice after lethal irradiation (7.5 Gy). It was found that treatment with rhIGF-I not only could increase the frequency of Sca-1+ cells in bone marrow harvested at Day 14 after irradiation, but also it could decrease the apoptosis of mononuclear cells induced by irradiation as measured by flow cytometry, suggesting that rhIGF-I may mediate its effects primarily through promoting hematopoietic stem cell/progenitor survival and protecting mononuclear cells from apoptosis after irradiation exposure. Moreover, we have found that rhIGF-I might facilitate thrombopoiesis in an indirect way. Our data demonstrated that rhIGF-I could promote overall hematopoietic recovery after ionizing radiation and reduce the mortality when administered immediately post lethal irradiation exposure." @default.
• W2168108114 created "2016-06-24" @default.
• W2168108114 creator A5001629068 @default.
• W2168108114 creator A5003377806 @default.
• W2168108114 creator A5017895753 @default.
• W2168108114 creator A5020405203 @default.
• W2168108114 creator A5034808877 @default.
• W2168108114 creator A5040931420 @default.
• W2168108114 creator A5043858190 @default.
• W2168108114 creator A5056522759 @default.
• W2168108114 creator A5060037184 @default.
• W2168108114 creator A5060964483 @default.
• W2168108114 date "2012-06-14" @default.
• W2168108114 modified "2023-10-17" @default.
• W2168108114 title "Subcutaneous administration of rhIGF-I post irradiation exposure enhances hematopoietic recovery and survival in BALB/c mice" @default.
• W2168108114 cites W1935861295 @default.
• W2168108114 cites W1973222840 @default.
• W2168108114 cites W1995855712 @default.
• W2168108114 cites W2009465370 @default.
• W2168108114 cites W2013190303 @default.
• W2168108114 cites W2024969918 @default.
• W2168108114 cites W2041672597 @default.
• W2168108114 cites W2052081532 @default.
• W2168108114 cites W2066718551 @default.
• W2168108114 cites W2075351155 @default.
• W2168108114 cites W2078031944 @default.
• W2168108114 cites W2086650050 @default.
• W2168108114 cites W2091660146 @default.
• W2168108114 cites W2091998318 @default.
• W2168108114 cites W2092328498 @default.
• W2168108114 cites W2094999001 @default.
• W2168108114 cites W2100489287 @default.
• W2168108114 cites W2101850049 @default.
• W2168108114 cites W2103486381 @default.
• W2168108114 cites W2115214722 @default.
• W2168108114 cites W2120583434 @default.
• W2168108114 cites W2123270583 @default.
• W2168108114 cites W2143386195 @default.
• W2168108114 cites W2157091913 @default.
• W2168108114 cites W2159030449 @default.
• W2168108114 cites W2408126077 @default.
• W2168108114 cites W4243395136 @default.
• W2168108114 cites W4254312338 @default.
• W2168108114 doi "https://doi.org/10.1093/jrr/rrs029" @default.
• W2168108114 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3393355" @default.
• W2168108114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22843623" @default.
• W2168108114 hasPublicationYear "2012" @default.
• W2168108114 type Work @default.
• W2168108114 sameAs 2168108114 @default.
• W2168108114 citedByCount "8" @default.
• W2168108114 countsByYear W21681081142013 @default.
• W2168108114 countsByYear W21681081142014 @default.
• W2168108114 countsByYear W21681081142015 @default.
• W2168108114 countsByYear W21681081142018 @default.
• W2168108114 countsByYear W21681081142021 @default.
• W2168108114 countsByYear W21681081142022 @default.
• W2168108114 crossrefType "journal-article" @default.
• W2168108114 hasAuthorship W2168108114A5001629068 @default.
• W2168108114 hasAuthorship W2168108114A5003377806 @default.
• W2168108114 hasAuthorship W2168108114A5017895753 @default.
• W2168108114 hasAuthorship W2168108114A5020405203 @default.
• W2168108114 hasAuthorship W2168108114A5034808877 @default.
• W2168108114 hasAuthorship W2168108114A5040931420 @default.
• W2168108114 hasAuthorship W2168108114A5043858190 @default.
• W2168108114 hasAuthorship W2168108114A5056522759 @default.
• W2168108114 hasAuthorship W2168108114A5060037184 @default.
• W2168108114 hasAuthorship W2168108114A5060964483 @default.
• W2168108114 hasBestOaLocation W21681081141 @default.
• W2168108114 hasConcept C109159458 @default.
• W2168108114 hasConcept C126322002 @default.
• W2168108114 hasConcept C137061746 @default.
• W2168108114 hasConcept C16685009 @default.
• W2168108114 hasConcept C190283241 @default.
• W2168108114 hasConcept C201750760 @default.
• W2168108114 hasConcept C202751555 @default.
• W2168108114 hasConcept C203014093 @default.
• W2168108114 hasConcept C2776694085 @default.
• W2168108114 hasConcept C2776755627 @default.
• W2168108114 hasConcept C2778880498 @default.
• W2168108114 hasConcept C2780007613 @default.
• W2168108114 hasConcept C28328180 @default.
• W2168108114 hasConcept C502942594 @default.
• W2168108114 hasConcept C553184892 @default.
• W2168108114 hasConcept C55493867 @default.
• W2168108114 hasConcept C71924100 @default.
• W2168108114 hasConcept C86803240 @default.
• W2168108114 hasConcept C95444343 @default.
• W2168108114 hasConcept C98274493 @default.
• W2168108114 hasConceptScore W2168108114C109159458 @default.
• W2168108114 hasConceptScore W2168108114C126322002 @default.
• W2168108114 hasConceptScore W2168108114C137061746 @default.
• W2168108114 hasConceptScore W2168108114C16685009 @default.
• W2168108114 hasConceptScore W2168108114C190283241 @default.
• W2168108114 hasConceptScore W2168108114C201750760 @default.
• W2168108114 hasConceptScore W2168108114C202751555 @default.
• W2168108114 hasConceptScore W2168108114C203014093 @default.
• W2168108114 hasConceptScore W2168108114C2776694085 @default.
• W2168108114 hasConceptScore W2168108114C2776755627 @default.

• next