Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168168020> ?p ?o ?g. }
- W2168168020 endingPage "3786" @default.
- W2168168020 startingPage "3779" @default.
- W2168168020 abstract "ABSTRACT To identify secreted virulence factors involved in bacterial wilt disease caused by the phytopathogen Ralstonia solanacearum , we mutated tatC , a key component of the t win- a rginine t ranslocation (Tat) secretion system. The R. solanacearum tatC mutation was pleiotropic; its phenotypes included defects in cell division, nitrate utilization, polygalacturonase activity, membrane stability, and growth in plant tissue. Bioinformatic analysis of the R. solanacearum strain GMI1000 genome predicted that this pathogen secretes 70 proteins via the Tat system. The R. solanacearum tatC strain was severely attenuated in its ability to cause disease, killing just over 50% of tomato plants in a naturalistic soil soak assay where the wild-type parent killed 100% of the plants. This result suggested that elements of the Tat secretome may be novel bacterial wilt virulence factors. To identify contributors to R. solanacearum virulence, we cloned and mutated three genes whose products are predicted to be secreted by the Tat system: RSp1521, encoding a predicted AcvB-like protein, and two genes, RSc1651 and RSp1575, that were identified as upregulated in planta by an in vivo expression technology screen. The RSc1651 mutant had wild-type virulence on tomato plants. However, mutants lacking either RSp1521, which appears to be involved in acid tolerance, or RSp1575, which encodes a possible amino acid binding protein, were significantly reduced in virulence on tomato plants. Additional bacterial wilt virulence factors may be found in the Tat secretome." @default.
- W2168168020 created "2016-06-24" @default.
- W2168168020 creator A5000037813 @default.
- W2168168020 creator A5008722699 @default.
- W2168168020 creator A5047127801 @default.
- W2168168020 creator A5071251602 @default.
- W2168168020 date "2007-06-15" @default.
- W2168168020 modified "2023-10-10" @default.
- W2168168020 title "Using the <i>Ralstonia solanacearum</i> Tat Secretome To Identify Bacterial Wilt Virulence Factors" @default.
- W2168168020 cites W1497159338 @default.
- W2168168020 cites W1498516814 @default.
- W2168168020 cites W1527005697 @default.
- W2168168020 cites W1529252218 @default.
- W2168168020 cites W1553772657 @default.
- W2168168020 cites W1663999974 @default.
- W2168168020 cites W1928256379 @default.
- W2168168020 cites W1941292022 @default.
- W2168168020 cites W1963898336 @default.
- W2168168020 cites W1980218465 @default.
- W2168168020 cites W1983311630 @default.
- W2168168020 cites W1984654391 @default.
- W2168168020 cites W2002575158 @default.
- W2168168020 cites W2005211587 @default.
- W2168168020 cites W2006990204 @default.
- W2168168020 cites W2018599288 @default.
- W2168168020 cites W203476929 @default.
- W2168168020 cites W2042620330 @default.
- W2168168020 cites W2057533316 @default.
- W2168168020 cites W2074439439 @default.
- W2168168020 cites W2077640701 @default.
- W2168168020 cites W2093128208 @default.
- W2168168020 cites W2116239375 @default.
- W2168168020 cites W2122351989 @default.
- W2168168020 cites W2123243522 @default.
- W2168168020 cites W2132417094 @default.
- W2168168020 cites W2133542385 @default.
- W2168168020 cites W2135710441 @default.
- W2168168020 cites W2135771899 @default.
- W2168168020 cites W2137673847 @default.
- W2168168020 cites W2137840411 @default.
- W2168168020 cites W2139374192 @default.
- W2168168020 cites W2142401436 @default.
- W2168168020 cites W2142479580 @default.
- W2168168020 cites W2151100831 @default.
- W2168168020 cites W2151725418 @default.
- W2168168020 cites W2325246960 @default.
- W2168168020 cites W2325945024 @default.
- W2168168020 cites W2328483020 @default.
- W2168168020 cites W4235408015 @default.
- W2168168020 doi "https://doi.org/10.1128/aem.02999-06" @default.
- W2168168020 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1932711" @default.
- W2168168020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17468289" @default.
- W2168168020 hasPublicationYear "2007" @default.
- W2168168020 type Work @default.
- W2168168020 sameAs 2168168020 @default.
- W2168168020 citedByCount "32" @default.
- W2168168020 countsByYear W21681680202013 @default.
- W2168168020 countsByYear W21681680202014 @default.
- W2168168020 countsByYear W21681680202015 @default.
- W2168168020 countsByYear W21681680202016 @default.
- W2168168020 countsByYear W21681680202017 @default.
- W2168168020 countsByYear W21681680202018 @default.
- W2168168020 countsByYear W21681680202019 @default.
- W2168168020 countsByYear W21681680202020 @default.
- W2168168020 countsByYear W21681680202022 @default.
- W2168168020 countsByYear W21681680202023 @default.
- W2168168020 crossrefType "journal-article" @default.
- W2168168020 hasAuthorship W2168168020A5000037813 @default.
- W2168168020 hasAuthorship W2168168020A5008722699 @default.
- W2168168020 hasAuthorship W2168168020A5047127801 @default.
- W2168168020 hasAuthorship W2168168020A5071251602 @default.
- W2168168020 hasBestOaLocation W21681680201 @default.
- W2168168020 hasConcept C104317684 @default.
- W2168168020 hasConcept C130211564 @default.
- W2168168020 hasConcept C143065580 @default.
- W2168168020 hasConcept C2776460866 @default.
- W2168168020 hasConcept C2776678335 @default.
- W2168168020 hasConcept C2779002231 @default.
- W2168168020 hasConcept C2780675535 @default.
- W2168168020 hasConcept C54355233 @default.
- W2168168020 hasConcept C59822182 @default.
- W2168168020 hasConcept C60987743 @default.
- W2168168020 hasConcept C86803240 @default.
- W2168168020 hasConcept C89423630 @default.
- W2168168020 hasConceptScore W2168168020C104317684 @default.
- W2168168020 hasConceptScore W2168168020C130211564 @default.
- W2168168020 hasConceptScore W2168168020C143065580 @default.
- W2168168020 hasConceptScore W2168168020C2776460866 @default.
- W2168168020 hasConceptScore W2168168020C2776678335 @default.
- W2168168020 hasConceptScore W2168168020C2779002231 @default.
- W2168168020 hasConceptScore W2168168020C2780675535 @default.
- W2168168020 hasConceptScore W2168168020C54355233 @default.
- W2168168020 hasConceptScore W2168168020C59822182 @default.
- W2168168020 hasConceptScore W2168168020C60987743 @default.
- W2168168020 hasConceptScore W2168168020C86803240 @default.
- W2168168020 hasConceptScore W2168168020C89423630 @default.
- W2168168020 hasIssue "12" @default.
- W2168168020 hasLocation W21681680201 @default.