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- W2168191036 abstract "OBJECTIVE: Our Center recommends ICSI on half of retrieved oocytes to lower the risk of fertilization failure in patients with primary infertility, and in women > 38 years of age who are at greater risk for poor oocyte quality and fewer oocyte numbers post controlled ovarian hyperstimulation. DESIGN: This prospective case cohort study compared the fertilization rates in poor and normal quality sibling oocytes from couples with primary infertility inseminated by ICSI or IVF. MATERIALS AND METHODS: All patients presenting for assisted reproductive treatment with primary infertility between January 2007 and October 2009, were invited to participate in this study. They were separated in two groups: Group 1: patients with poor oocyte quality determined at oocyte retrieval and Group 2: patients with normal oocyte morphology. Sibling oocytes from each patient were randomly assigned for insemination by ICSI or by IVF. The Wilcoxon Signed Ranks non-parametric statistical test was used to determine significant differences, where P <0.05 was considered significant. RESULTS: 100 patients with a total of 988 oocytes were evaluated in this study. No statistically significant difference was observed between the fertilization rate after ICSI or IVF in Group 1. IVF showed significantly higher fertilization rates than ICSI in Group 2 in the 38-40 age group. CONCLUSION: There was no difference in the fertilization rates between ICSI and IVF in primary infertility patients with poor oocyte quality. This study demonstrates that conventional IVF as a method for insemination is equally as effective as ICSI in predicted poor outcome patients. IVF showed increased fertilization rates in normal morphology oocytes on primary fertility patients in the age group 38-40." @default.
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- W2168191036 date "2010-09-01" @default.
- W2168191036 modified "2023-10-14" @default.
- W2168191036 title "Fertilization rate of sibling oocytes after intracytoplasmic sperm injection (ICSI) or in vitro fertilization (IVF) on primary infertility patients" @default.
- W2168191036 doi "https://doi.org/10.1016/j.fertnstert.2010.07.955" @default.
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