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- W2168325635 abstract "Entry of HIV-1 into human cells requires CD4 and a coreceptor. CC-ehemokine receptor 5 (CCR-5) is the common coreceptor for macrophage-tropic, non-syncytium inducing (NSI) HIV-1 strains that predominate during initial infection. A 32 base-pair deletion (▵32) in the CCR5 coding region results in a non-functional receptor. 1 Dean M Carrington M Winkler C et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Science. 1996; 273: 1856-1862 Crossref PubMed Scopus (2178) Google Scholar We describe a patient who was homozygous for CCR5▵32, but nonetheless became infected with HIV-1." @default.
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- W2168325635 date "1997-04-01" @default.
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- W2168325635 title "HIV-1 infection in a man homozygous for CCR5▵32" @default.
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- W2168325635 doi "https://doi.org/10.1016/s0140-6736(97)24017-1" @default.
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