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• W2168326617 abstract "Molecular surveillance of multidrug-resistant tuberculosis (MDR TB) was implemented in Europe as case reporting in 2005. For all new MDR TB cases detected from January 2003 through June 2007, countries reported case-based epidemiologic data and DNA fingerprint patterns of MDR TB strains when available. International clusters were detected and analyzed. From 2003 through mid-2007 in Europe, 2,494 cases of MDR TB were reported from 24 European countries. Epidemiologic and molecular data were linked for 593 (39%) cases, and 672 insertion sequence 6110 DNA fingerprint patterns were reported from 19 countries. Of these patterns, 288 (43%) belonged to 18 European clusters; 7 clusters (242/288 cases, 84%) were characterized by strains of the Beijing genotype family, including the largest cluster (175/288 cases, 61%). Both clustering and the Beijing genotype were associated with strains originating in eastern European countries. Molecular cluster detection contributes to identification of transmission profile, risk factors, and control measures." @default.
• W2168326617 created "2016-06-24" @default.
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• W2168326617 date "2009-07-01" @default.
• W2168326617 modified "2023-09-26" @default.
• W2168326617 title "Clusters of Multidrug-Resistant<i>Mycobacterium tuberculosis</i>Cases, Europe" @default.
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• W2168326617 doi "https://doi.org/10.3201/eid1507.080994" @default.
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