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- W2168348516 abstract "The similarities between brain tumor stem cells and neural stem cells suggest a possible stem cell origin of tumorigenesis. Recently, cells with features of stem cells have been observed in lesions of adult and pediatric cortical dysplasia (CD). Given the evidence for a close relationship between CD and certain brain tumors, together with the finding that CD neural stem cells/progenitors are abnormally developed, we propose that CD is a possible substrate for brain tumors. The neural stem cells/progenitors in CD have accumulating abnormalities, and these abnormal stem/progenitor cells may be the initiating, transformed cells of brain tumors, when subsequently exposed to a carcinogen." @default.
- W2168348516 created "2016-06-24" @default.
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- W2168348516 date "2012-03-01" @default.
- W2168348516 modified "2023-09-25" @default.
- W2168348516 title "Cortical dysplasia: a possible substrate for brain tumors" @default.
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- W2168348516 doi "https://doi.org/10.2217/fon.12.6" @default.
- W2168348516 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4788700" @default.
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- W2168348516 hasPublicationYear "2012" @default.
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