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- W2168405937 abstract "Inflammation is an adaptive response of the immune system to tissue malfunction or homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) are frequently applied to treat varieties of inflammatory diseases but are associated with gastrointestinal, cardiovascular, and kidney side effects. Developing more effective and less toxic agents remain a challenge for pharmaceutical chemist due to the complexity of the different inflammatory processes. Alkaloids are widely distributed in plants with diverse anti-inflammatory activities, providing various potential lead compounds or candidates for the design and discovery of new anti-inflammatory drug candidates. Therefore, re-examining the anti-inflammatory alkaloid natural products is advisable, bringing more opportunities. In this review, we summarized and described the recent advances of natural alkaloids with anti-inflammatory activities and possible mechanisms in the period from 2009 to 2020. It is hoped that this review of anti-inflammatory alkaloids can provide new ideas for researchers engaged in the related fields and potential lead compounds for the discovery of anti-inflammatory drugs." @default.
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- W2168405937 date "1979-01-01" @default.
- W2168405937 modified "2023-09-26" @default.
- W2168405937 title "Preparation and properties of the tetrakis[tetrathiomolybdato(VI)-μ3-sulfidoiron] Cluster, [Fe4Mo4S20]6−" @default.
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- W2168405937 doi "https://doi.org/10.1016/s0020-1693(00)89354-8" @default.
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