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- W2168490037 abstract "The biotrasformation of the tetrahydrofuran lignan, (-)-grandisin, by the endophitic fungus Phomopsis sp, obtained from Viguiera arenaria, led to the formation of a new compound determined as 3,4-dimethyl-2-(4'-hydroxy-3',5'-dimethoxyphenyl)-5-methoxy-tetrahydrofuran. The metabolite was evaluated against the parasite Trypanosoma cruzi, the causative agent of Chagas's disease, and showed a trypanocidal activity (IC50 9.8 μmol L-1) similar to the natural precursor (IC50 3.7 μmol L-1)." @default.
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- W2168490037 date "2009-01-01" @default.
- W2168490037 modified "2023-09-23" @default.
- W2168490037 title "Biotransformation of a tetrahydrofuran lignan by the endophytic fungus Phomopsis Sp." @default.
- W2168490037 doi "https://doi.org/10.1590/s0103-50532009000100029" @default.
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