Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168537112> ?p ?o ?g. }
- W2168537112 endingPage "157" @default.
- W2168537112 startingPage "149" @default.
- W2168537112 abstract "The phenotype and fate of fetal microchimeric cells transfered into the maternal circulation during pregnancy are not well described. Since progenitors from distal sites mobilize during wound healing, we analyzed the recruitment and plasticity of fetal progenitors into maternal wounds. Wounds were generated on normal and bleomycin-induced fibrotic skin of parous or pregnant wild-type females with fluorescent GFP(+) fetuses. Analyses were performed on skin and blood specimens through PCR, immunohistochemistry, and flow cytometry. Controls consisted of parous and pregnant females without wounds and virgin females with wounds. Fetal cells were detected in all skin specimens of parous mice as long as healing was not achieved. During early stages of wound healing, fetal cells expressed mainly leukocyte markers, while in later phases endothelial markers prevailed. Fetally derived vessels connected to maternal circulation were also found, demonstrating the transfer of fetal endothelial progenitor cells. Wounding mobilized fetal CD34(+)ckit(-) cells into the blood during pregnancy. Most of this population was CD11b(-)VEGFR2(-). Another part was CD11b(+) with a fraction expressing VEGFR2. VEGFa-spiked Matrigel plugs partially mimicked this fetal progenitor recruitment and mobilization into the blood. In summary, fetal cells that mobilize in response to wounding are mainly progenitor cells and participate in angiogenesis and inflammation." @default.
- W2168537112 created "2016-06-24" @default.
- W2168537112 creator A5016310649 @default.
- W2168537112 creator A5023991384 @default.
- W2168537112 creator A5025412787 @default.
- W2168537112 creator A5035641630 @default.
- W2168537112 creator A5043446323 @default.
- W2168537112 creator A5084151252 @default.
- W2168537112 date "2011-10-05" @default.
- W2168537112 modified "2023-10-18" @default.
- W2168537112 title "Fetal progenitor cells naturally transferred through pregnancy participate in inflammation and angiogenesis during wound healing" @default.
- W2168537112 cites W1566903555 @default.
- W2168537112 cites W1835179263 @default.
- W2168537112 cites W1920534265 @default.
- W2168537112 cites W1967669991 @default.
- W2168537112 cites W1975975018 @default.
- W2168537112 cites W1985982499 @default.
- W2168537112 cites W1989483643 @default.
- W2168537112 cites W1989911676 @default.
- W2168537112 cites W1993854911 @default.
- W2168537112 cites W1996385150 @default.
- W2168537112 cites W2001935341 @default.
- W2168537112 cites W2008062232 @default.
- W2168537112 cites W2008552527 @default.
- W2168537112 cites W2008559248 @default.
- W2168537112 cites W2010152981 @default.
- W2168537112 cites W2021680265 @default.
- W2168537112 cites W2074467657 @default.
- W2168537112 cites W2079204371 @default.
- W2168537112 cites W2091879759 @default.
- W2168537112 cites W2092468445 @default.
- W2168537112 cites W2094283542 @default.
- W2168537112 cites W2095132685 @default.
- W2168537112 cites W2097488055 @default.
- W2168537112 cites W2099312448 @default.
- W2168537112 cites W2121058001 @default.
- W2168537112 cites W2132837577 @default.
- W2168537112 cites W2138831748 @default.
- W2168537112 cites W2145639716 @default.
- W2168537112 cites W2154909636 @default.
- W2168537112 cites W2161595664 @default.
- W2168537112 cites W2172294959 @default.
- W2168537112 cites W2288233919 @default.
- W2168537112 cites W2325727928 @default.
- W2168537112 doi "https://doi.org/10.1096/fj.11-180695" @default.
- W2168537112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21974929" @default.
- W2168537112 hasPublicationYear "2011" @default.
- W2168537112 type Work @default.
- W2168537112 sameAs 2168537112 @default.
- W2168537112 citedByCount "51" @default.
- W2168537112 countsByYear W21685371122012 @default.
- W2168537112 countsByYear W21685371122013 @default.
- W2168537112 countsByYear W21685371122014 @default.
- W2168537112 countsByYear W21685371122015 @default.
- W2168537112 countsByYear W21685371122016 @default.
- W2168537112 countsByYear W21685371122017 @default.
- W2168537112 countsByYear W21685371122018 @default.
- W2168537112 countsByYear W21685371122019 @default.
- W2168537112 countsByYear W21685371122020 @default.
- W2168537112 countsByYear W21685371122021 @default.
- W2168537112 countsByYear W21685371122022 @default.
- W2168537112 countsByYear W21685371122023 @default.
- W2168537112 crossrefType "journal-article" @default.
- W2168537112 hasAuthorship W2168537112A5016310649 @default.
- W2168537112 hasAuthorship W2168537112A5023991384 @default.
- W2168537112 hasAuthorship W2168537112A5025412787 @default.
- W2168537112 hasAuthorship W2168537112A5035641630 @default.
- W2168537112 hasAuthorship W2168537112A5043446323 @default.
- W2168537112 hasAuthorship W2168537112A5084151252 @default.
- W2168537112 hasConcept C10205521 @default.
- W2168537112 hasConcept C126322002 @default.
- W2168537112 hasConcept C142724271 @default.
- W2168537112 hasConcept C162834538 @default.
- W2168537112 hasConcept C16685009 @default.
- W2168537112 hasConcept C172680121 @default.
- W2168537112 hasConcept C201750760 @default.
- W2168537112 hasConcept C203014093 @default.
- W2168537112 hasConcept C2778271429 @default.
- W2168537112 hasConcept C2779234561 @default.
- W2168537112 hasConcept C2780269544 @default.
- W2168537112 hasConcept C2780394083 @default.
- W2168537112 hasConcept C28328180 @default.
- W2168537112 hasConcept C2908647359 @default.
- W2168537112 hasConcept C54355233 @default.
- W2168537112 hasConcept C60781801 @default.
- W2168537112 hasConcept C71924100 @default.
- W2168537112 hasConcept C86803240 @default.
- W2168537112 hasConcept C95444343 @default.
- W2168537112 hasConcept C99454951 @default.
- W2168537112 hasConceptScore W2168537112C10205521 @default.
- W2168537112 hasConceptScore W2168537112C126322002 @default.
- W2168537112 hasConceptScore W2168537112C142724271 @default.
- W2168537112 hasConceptScore W2168537112C162834538 @default.
- W2168537112 hasConceptScore W2168537112C16685009 @default.
- W2168537112 hasConceptScore W2168537112C172680121 @default.
- W2168537112 hasConceptScore W2168537112C201750760 @default.
- W2168537112 hasConceptScore W2168537112C203014093 @default.
- W2168537112 hasConceptScore W2168537112C2778271429 @default.