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• W2168597007 abstract "Hagyományos kezelésre refrakter, fistulás Crohn-betegek kezelésében a chimer antitumornekrózis-faktor-alfa- (infliximab-) terápia igen hatékony, bár a betegek egy részében infliximabrezisztencia alakulhat ki. A szerzők egy infliximabrezisztens, 12 éves Crohn-beteg fiú esetét ismertetik, akinek luminális gyulladása mellett 3 aktív perianalis fistulája is volt. Teljesen humanizált antitumornekrózis-faktor-alfa- (adalimumab-) kezelést követően a 10. héten a fistulák bezáródtak, a korábbi magas aktivitási index normalizálódott. Validált életminőségi mutatók szintén szignifikánsan javultak. Az eset alapján infliximabrezisztens Crohn-beteg gyermeknél az adalimumabterápia sikerrel alkalmazható." @default.
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• W2168597007 date "2009-10-01" @default.
• W2168597007 modified "2023-10-17" @default.
• W2168597007 title "Adalimumab treatment in infliximab resistant pediatric patient with Crohn’s disease" @default.
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• W2168597007 doi "https://doi.org/10.1556/oh.2009.28731" @default.
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