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• W2168609055 abstract "Purpose To prospectively investigate the prevalence of fat deposition in chronic myocardial infarction (MI) by using magnetic resonance (MR) fat-water separation imaging with sampling of the entire left ventricular (LV) myocardium. A subsidiary aim was to determine the relationship between LV fat deposition and scar characteristics, as well as regional and global cardiac functional parameters. Materials and Methods Twenty-five patients with LV MI were evaluated in this prospective institutional review board–approved, Health Insurance Portability and Accountability Act–compliant study after they provided written informed consent. A 1.5-T MR system was used to perform volumetric cine, fat-sensitive, and late gadolinium-enhanced (LGE) infarct imaging. Water-fat separation was performed by using a three-point Dixon reconstruction from in- and opposed-phase black-blood gradient-echo images. Fat deposition location was compared with LGE infarct imaging by using a 17-segment model. Global and regional functional variables, LGE volumes, and fat deposition were compared by using the Pearson correlation, Student t test, and multiple regression. Results A fat deposition prevalence of 68% was found in areas of chronic MI. The patients with fat deposition had larger infarctions (30.0 mL ± 15.1 [standard deviation] vs 14.8 mL ± 6.1; P = .002), decreased wall thickening (2.3% ± 20.0 vs 37.8% ± 34.4; P = .003), and impaired endocardial wall motion (2.9 mm ± 2.0 vs 5.8 mm ± 2.6; P = .007). The volume of fat deposition was correlated with infarct volume, LV ejection fraction, LV end-diastolic volume index, and LV end-systolic volume index. Conclusion There is a high prevalence of fat deposition in healed MI. It is associated with post-infarction characteristics including infarct volume, LV mass, wall thickness, wall thickening, and wall motion. © RSNA, 2009" @default.
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• W2168609055 date "2009-10-01" @default.
• W2168609055 modified "2023-10-03" @default.
• W2168609055 title "Myocardial Fat Deposition after Left Ventricular Myocardial Infarction: Assessment by Using MR Water-Fat Separation Imaging" @default.
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• W2168609055 doi "https://doi.org/10.1148/radiol.2532082290" @default.
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