Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168692743> ?p ?o ?g. }
- W2168692743 abstract "Abstract Background ANGUSTIFOLIA (AN), one of the CtBP family proteins, plays a major role in microtubule-dependent cell morphogenesis. Microarray analysis of mammalian AN homologs suggests that AN might function as a transcriptional activator and regulator of a wide range of genes. Genetic characterization of AN mutants suggests that AN might be involved in multiple biological processes beyond cell morphology regulation. Results Using a reverse genetic approach, we provide in this paper the genetic, biochemical, and physiological evidence for ANGUSTIFOLIA’s role in other new biological functions such as abiotic and biotic stress response in higher plants. The T-DNA knockout an - t1 mutant exhibits not only all the phenotypes of previously described angustifolia null mutants, but also copes better than wild type under dehydration and pathogen attack. The stress tolerance is accompanied by a steady-state modulation of cellular H 2 O 2 content, malondialdehyde (MDA) derived from cellular lipid peroxidation, and over-expression of stress responsive genes. Our results indicate that ANGUSTIFOLIA functions beyond cell morphology control through direct or indirect functional protein interaction networks mediating other biological processes such as drought and pathogen attacks. Conclusions Our results indicate that the ANGUSTIFOLIA gene participates in several biochemical pathways controlling cell morphogenesis, abiotic, and biotic stress responses in higher plants. Our results suggest that the in vivo function of plant ANGUSTIFOLIA has been overlooked and it needs to be further studied beyond microtubule-dependent cell morphogenesis." @default.
- W2168692743 created "2016-06-24" @default.
- W2168692743 creator A5016165983 @default.
- W2168692743 creator A5020553626 @default.
- W2168692743 creator A5021741541 @default.
- W2168692743 creator A5025695630 @default.
- W2168692743 creator A5027849577 @default.
- W2168692743 creator A5056933328 @default.
- W2168692743 creator A5067194160 @default.
- W2168692743 creator A5091879686 @default.
- W2168692743 date "2013-05-14" @default.
- W2168692743 modified "2023-10-06" @default.
- W2168692743 title "The cell morphogenesis ANGUSTIFOLIA (AN) gene, a plant homolog of CtBP/BARS, is involved in abiotic and biotic stress response in higher plants" @default.
- W2168692743 cites W1526340496 @default.
- W2168692743 cites W1665675901 @default.
- W2168692743 cites W1964775981 @default.
- W2168692743 cites W1964796504 @default.
- W2168692743 cites W1987272585 @default.
- W2168692743 cites W1995774065 @default.
- W2168692743 cites W1998613525 @default.
- W2168692743 cites W2005019117 @default.
- W2168692743 cites W2007601852 @default.
- W2168692743 cites W2023093864 @default.
- W2168692743 cites W2024301699 @default.
- W2168692743 cites W2042980615 @default.
- W2168692743 cites W2048122656 @default.
- W2168692743 cites W2057146784 @default.
- W2168692743 cites W2059890422 @default.
- W2168692743 cites W2076826701 @default.
- W2168692743 cites W2082514530 @default.
- W2168692743 cites W2088256976 @default.
- W2168692743 cites W2094952033 @default.
- W2168692743 cites W2102961872 @default.
- W2168692743 cites W2109230943 @default.
- W2168692743 cites W2118531941 @default.
- W2168692743 cites W2119832055 @default.
- W2168692743 cites W2120394608 @default.
- W2168692743 cites W2123763464 @default.
- W2168692743 cites W2136968773 @default.
- W2168692743 cites W2151240250 @default.
- W2168692743 cites W2151778156 @default.
- W2168692743 cites W4237870379 @default.
- W2168692743 doi "https://doi.org/10.1186/1471-2229-13-79" @default.
- W2168692743 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3663690" @default.
- W2168692743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23672620" @default.
- W2168692743 hasPublicationYear "2013" @default.
- W2168692743 type Work @default.
- W2168692743 sameAs 2168692743 @default.
- W2168692743 citedByCount "21" @default.
- W2168692743 countsByYear W21686927432013 @default.
- W2168692743 countsByYear W21686927432014 @default.
- W2168692743 countsByYear W21686927432015 @default.
- W2168692743 countsByYear W21686927432017 @default.
- W2168692743 countsByYear W21686927432018 @default.
- W2168692743 countsByYear W21686927432019 @default.
- W2168692743 countsByYear W21686927432020 @default.
- W2168692743 countsByYear W21686927432021 @default.
- W2168692743 countsByYear W21686927432022 @default.
- W2168692743 countsByYear W21686927432023 @default.
- W2168692743 crossrefType "journal-article" @default.
- W2168692743 hasAuthorship W2168692743A5016165983 @default.
- W2168692743 hasAuthorship W2168692743A5020553626 @default.
- W2168692743 hasAuthorship W2168692743A5021741541 @default.
- W2168692743 hasAuthorship W2168692743A5025695630 @default.
- W2168692743 hasAuthorship W2168692743A5027849577 @default.
- W2168692743 hasAuthorship W2168692743A5056933328 @default.
- W2168692743 hasAuthorship W2168692743A5067194160 @default.
- W2168692743 hasAuthorship W2168692743A5091879686 @default.
- W2168692743 hasBestOaLocation W21686927431 @default.
- W2168692743 hasConcept C104317684 @default.
- W2168692743 hasConcept C132215390 @default.
- W2168692743 hasConcept C143065580 @default.
- W2168692743 hasConcept C146926016 @default.
- W2168692743 hasConcept C18903297 @default.
- W2168692743 hasConcept C40692019 @default.
- W2168692743 hasConcept C54355233 @default.
- W2168692743 hasConcept C59822182 @default.
- W2168692743 hasConcept C86803240 @default.
- W2168692743 hasConcept C89519541 @default.
- W2168692743 hasConcept C95444343 @default.
- W2168692743 hasConceptScore W2168692743C104317684 @default.
- W2168692743 hasConceptScore W2168692743C132215390 @default.
- W2168692743 hasConceptScore W2168692743C143065580 @default.
- W2168692743 hasConceptScore W2168692743C146926016 @default.
- W2168692743 hasConceptScore W2168692743C18903297 @default.
- W2168692743 hasConceptScore W2168692743C40692019 @default.
- W2168692743 hasConceptScore W2168692743C54355233 @default.
- W2168692743 hasConceptScore W2168692743C59822182 @default.
- W2168692743 hasConceptScore W2168692743C86803240 @default.
- W2168692743 hasConceptScore W2168692743C89519541 @default.
- W2168692743 hasConceptScore W2168692743C95444343 @default.
- W2168692743 hasIssue "1" @default.
- W2168692743 hasLocation W21686927431 @default.
- W2168692743 hasLocation W21686927432 @default.
- W2168692743 hasLocation W21686927433 @default.
- W2168692743 hasLocation W21686927434 @default.
- W2168692743 hasLocation W21686927435 @default.
- W2168692743 hasOpenAccess W2168692743 @default.
- W2168692743 hasPrimaryLocation W21686927431 @default.
- W2168692743 hasRelatedWork W1599566291 @default.