Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168711532> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2168711532 endingPage "426" @default.
- W2168711532 startingPage "418" @default.
- W2168711532 abstract "A number of polycyclic aromatic hydrocarbons (PAHs) have been shown to be toxicants, and induce carcinogenic and immunotoxic effects. As a model PAH agent, 7,12-dimethylbenz[a]anthracene (DMBA) was the strongest one tested in terms of its biological activities and biotransformation. A new and simple high-performance liquid chromatographic (HPLC) method with diode-array detection at 290 nm was developed and validated for monitoring of DMBA in different matrices (serum, liver and kidney) of rats orally treated with DMBA. Furthermore, the applicability of adsorptive transfer stripping voltammetry (AdTSV) on the pencil-lead graphite electrode to these samples was illustrated using our previously reported data for bulk aqueous solutions of DMBA. HPLC and AdTSV methods, which were compatible with each other, allowed DMBA to be detected down to the levels of 3.82x10-9 M (0.98 ppb) and 6.73x10-9 M (1.73 ppb), respectively. Olive oil solutions of DMBA in dose 50 mg/kg were orally administered. 60 days after a single dose of DMBA, its concentrations in these biological samples from rats were measured by means of both methods. Because of rapid biotransformation, DMBA could not be detected in serum. Only low levels of the compounds were deposited unchanged in kidney whereas its levels were considerably higher in liver. These methods were also applied to the assay whether there is an influence of the intake of aqueous extracts of Hypericum Perforatum L. plant on the parent DMBA levels accumulated in rat tissues." @default.
- W2168711532 created "2016-06-24" @default.
- W2168711532 creator A5035707124 @default.
- W2168711532 creator A5039993646 @default.
- W2168711532 creator A5059557793 @default.
- W2168711532 creator A5075193050 @default.
- W2168711532 creator A5084916438 @default.
- W2168711532 creator A5085656193 @default.
- W2168711532 date "2012-04-01" @default.
- W2168711532 modified "2023-10-11" @default.
- W2168711532 title "Determination of 7,12-Dimethylbenz[a]Anthracene in Orally Treated Rats by High-Performance Liquid Chromatography and Transfer Stripping Voltammetry" @default.
- W2168711532 doi "https://doi.org/10.2174/138620712800194440" @default.
- W2168711532 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22263862" @default.
- W2168711532 hasPublicationYear "2012" @default.
- W2168711532 type Work @default.
- W2168711532 sameAs 2168711532 @default.
- W2168711532 citedByCount "2" @default.
- W2168711532 countsByYear W21687115322017 @default.
- W2168711532 countsByYear W21687115322022 @default.
- W2168711532 crossrefType "journal-article" @default.
- W2168711532 hasAuthorship W2168711532A5035707124 @default.
- W2168711532 hasAuthorship W2168711532A5039993646 @default.
- W2168711532 hasAuthorship W2168711532A5059557793 @default.
- W2168711532 hasAuthorship W2168711532A5075193050 @default.
- W2168711532 hasAuthorship W2168711532A5084916438 @default.
- W2168711532 hasAuthorship W2168711532A5085656193 @default.
- W2168711532 hasConcept C104317684 @default.
- W2168711532 hasConcept C178790620 @default.
- W2168711532 hasConcept C179998833 @default.
- W2168711532 hasConcept C184651966 @default.
- W2168711532 hasConcept C185592680 @default.
- W2168711532 hasConcept C2776260934 @default.
- W2168711532 hasConcept C2778938436 @default.
- W2168711532 hasConcept C2779563022 @default.
- W2168711532 hasConcept C43617362 @default.
- W2168711532 hasConcept C55493867 @default.
- W2168711532 hasConcept C555283112 @default.
- W2168711532 hasConceptScore W2168711532C104317684 @default.
- W2168711532 hasConceptScore W2168711532C178790620 @default.
- W2168711532 hasConceptScore W2168711532C179998833 @default.
- W2168711532 hasConceptScore W2168711532C184651966 @default.
- W2168711532 hasConceptScore W2168711532C185592680 @default.
- W2168711532 hasConceptScore W2168711532C2776260934 @default.
- W2168711532 hasConceptScore W2168711532C2778938436 @default.
- W2168711532 hasConceptScore W2168711532C2779563022 @default.
- W2168711532 hasConceptScore W2168711532C43617362 @default.
- W2168711532 hasConceptScore W2168711532C55493867 @default.
- W2168711532 hasConceptScore W2168711532C555283112 @default.
- W2168711532 hasIssue "5" @default.
- W2168711532 hasLocation W21687115321 @default.
- W2168711532 hasLocation W21687115322 @default.
- W2168711532 hasOpenAccess W2168711532 @default.
- W2168711532 hasPrimaryLocation W21687115321 @default.
- W2168711532 hasRelatedWork W1554537892 @default.
- W2168711532 hasRelatedWork W1971815790 @default.
- W2168711532 hasRelatedWork W2033587424 @default.
- W2168711532 hasRelatedWork W2037807672 @default.
- W2168711532 hasRelatedWork W2092703933 @default.
- W2168711532 hasRelatedWork W2168444622 @default.
- W2168711532 hasRelatedWork W2414492442 @default.
- W2168711532 hasRelatedWork W2460918933 @default.
- W2168711532 hasRelatedWork W2573196299 @default.
- W2168711532 hasRelatedWork W628537020 @default.
- W2168711532 hasVolume "15" @default.
- W2168711532 isParatext "false" @default.
- W2168711532 isRetracted "false" @default.
- W2168711532 magId "2168711532" @default.
- W2168711532 workType "article" @default.