FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168712912> ?p ?o ?g. }

• W2168712912 endingPage "3572" @default.
• W2168712912 startingPage "3554" @default.
• W2168712912 abstract "Variations in cortical oscillations in the alpha (7-14 Hz) and beta (15-29 Hz) range have been correlated with attention, working memory, and stimulus detection. The mu rhythm recorded with magnetoencephalography (MEG) is a prominent oscillation generated by Rolandic cortex containing alpha and beta bands. Despite its prominence, the neural mechanisms regulating mu are unknown. We characterized the ongoing MEG mu rhythm from a localized source in the finger representation of primary somatosensory (SI) cortex. Subjects showed variation in the relative expression of mu-alpha or mu-beta, which were nonoverlapping for roughly 50% of their respective durations on single trials. To delineate the origins of this rhythm, a biophysically principled computational neural model of SI was developed, with distinct laminae, inhibitory and excitatory neurons, and feedforward (FF, representative of lemniscal thalamic drive) and feedback (FB, representative of higher-order cortical drive or input from nonlemniscal thalamic nuclei) inputs defined by the laminar location of their postsynaptic effects. The mu-alpha component was accurately modeled by rhythmic FF input at approximately 10-Hz. The mu-beta component was accurately modeled by the addition of approximately 10-Hz FB input that was nearly synchronous with the FF input. The relative dominance of these two frequencies depended on the delay between FF and FB drives, their relative input strengths, and stochastic changes in these variables. The model also reproduced key features of the impact of high prestimulus mu power on peaks in SI-evoked activity. For stimuli presented during high mu power, the model predicted enhancement in an initial evoked peak and decreased subsequent deflections. In agreement, the MEG-evoked responses showed an enhanced initial peak and a trend to smaller subsequent peaks. These data provide new information on the dynamics of the mu rhythm in humans and the model provides a novel mechanistic interpretation of this rhythm and its functional significance." @default.
• W2168712912 created "2016-06-24" @default.
• W2168712912 creator A5020315656 @default.
• W2168712912 creator A5041838549 @default.
• W2168712912 creator A5044501245 @default.
• W2168712912 creator A5049444333 @default.
• W2168712912 creator A5051619961 @default.
• W2168712912 creator A5075419685 @default.
• W2168712912 date "2009-12-01" @default.
• W2168712912 modified "2023-10-16" @default.
• W2168712912 title "Quantitative Analysis and Biophysically Realistic Neural Modeling of the MEG Mu Rhythm: Rhythmogenesis and Modulation of Sensory-Evoked Responses" @default.
• W2168712912 cites W1494230272 @default.
• W2168712912 cites W1542485919 @default.
• W2168712912 cites W1561090407 @default.
• W2168712912 cites W1596040508 @default.
• W2168712912 cites W1679402667 @default.
• W2168712912 cites W1936316516 @default.
• W2168712912 cites W1960123170 @default.
• W2168712912 cites W1968697559 @default.
• W2168712912 cites W1972328487 @default.
• W2168712912 cites W1977177901 @default.
• W2168712912 cites W1978386551 @default.
• W2168712912 cites W1981855363 @default.
• W2168712912 cites W1982538923 @default.
• W2168712912 cites W1984433170 @default.
• W2168712912 cites W1985646728 @default.
• W2168712912 cites W1986014504 @default.
• W2168712912 cites W1987333243 @default.
• W2168712912 cites W1987646177 @default.
• W2168712912 cites W1988387613 @default.
• W2168712912 cites W1989215993 @default.
• W2168712912 cites W1990157444 @default.
• W2168712912 cites W1993307163 @default.
• W2168712912 cites W1993684658 @default.
• W2168712912 cites W1993712292 @default.
• W2168712912 cites W1997531932 @default.
• W2168712912 cites W1997547724 @default.
• W2168712912 cites W1999567494 @default.
• W2168712912 cites W2002740781 @default.
• W2168712912 cites W2003877340 @default.
• W2168712912 cites W2004895652 @default.
• W2168712912 cites W2005364540 @default.
• W2168712912 cites W2007502604 @default.
• W2168712912 cites W2008053155 @default.
• W2168712912 cites W2008609531 @default.
• W2168712912 cites W2010341016 @default.
• W2168712912 cites W2010538751 @default.
• W2168712912 cites W2015525532 @default.
• W2168712912 cites W2016479629 @default.
• W2168712912 cites W2017325381 @default.
• W2168712912 cites W2020264699 @default.
• W2168712912 cites W2024560606 @default.
• W2168712912 cites W2027484750 @default.
• W2168712912 cites W2031212812 @default.
• W2168712912 cites W2032006156 @default.
• W2168712912 cites W2033616618 @default.
• W2168712912 cites W2034284926 @default.
• W2168712912 cites W2035314640 @default.
• W2168712912 cites W2037204517 @default.
• W2168712912 cites W2042619570 @default.
• W2168712912 cites W2043000233 @default.
• W2168712912 cites W2043552012 @default.
• W2168712912 cites W2043877765 @default.
• W2168712912 cites W2045986659 @default.
• W2168712912 cites W2047426925 @default.
• W2168712912 cites W2049585061 @default.
• W2168712912 cites W2050602205 @default.
• W2168712912 cites W2054775468 @default.
• W2168712912 cites W2055283560 @default.
• W2168712912 cites W2055651888 @default.
• W2168712912 cites W2056091956 @default.
• W2168712912 cites W2062876788 @default.
• W2168712912 cites W2063542323 @default.
• W2168712912 cites W2064064010 @default.
• W2168712912 cites W2064988592 @default.
• W2168712912 cites W2067327770 @default.
• W2168712912 cites W2074137442 @default.
• W2168712912 cites W2076112114 @default.
• W2168712912 cites W2084333685 @default.
• W2168712912 cites W2087406384 @default.
• W2168712912 cites W2091248976 @default.
• W2168712912 cites W2098406191 @default.
• W2168712912 cites W2098580305 @default.
• W2168712912 cites W2105902140 @default.
• W2168712912 cites W2106250137 @default.
• W2168712912 cites W2108197606 @default.
• W2168712912 cites W2112463907 @default.
• W2168712912 cites W2113279719 @default.
• W2168712912 cites W2117276688 @default.
• W2168712912 cites W2121324852 @default.
• W2168712912 cites W2122972758 @default.
• W2168712912 cites W2125802575 @default.
• W2168712912 cites W2129846302 @default.
• W2168712912 cites W2129868883 @default.
• W2168712912 cites W2129888386 @default.
• W2168712912 cites W2133280087 @default.
• W2168712912 cites W2133366903 @default.
• W2168712912 cites W2135396112 @default.

• next