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• W2168749824 abstract "Phenothiazinium dyes, and derivatives, were tested for toxicity to Escherichia coli and Staphylococcus aureus. The dyes were generally lipophilic (log P>1) and showed inherent dark toxicity (minimum lethal concentrations: 3.1–1000 µM). Dye illumination (total light dose of 3.15 J cm−1 over 30 min) led to up to eight-fold reductions in minimum lethal concentrations. Most of the illuminated dyes showed significant relative singlet oxygen yields (Φ′Δ: 0.18–1.35) suggesting a type II mechanism of generating a phototoxic response. Although generally up to six-fold more effective against S. aureus, the dyes tested efficiently killed E. coli and may be of particular use in combating Gram-negative pathogens." @default.
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• W2168749824 date "2003-10-01" @default.
• W2168749824 modified "2023-10-15" @default.
• W2168749824 title "The phototoxicity of phenothiazinium derivatives against<i>Escherichia coli</i>and<i>Staphylococcus aureus</i>" @default.
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• W2168749824 doi "https://doi.org/10.1016/s0928-8244(03)00173-1" @default.
• W2168749824 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14556991" @default.
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