Matches in SemOpenAlex for { <https://semopenalex.org/work/W2168951504> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2168951504 endingPage "546" @default.
- W2168951504 startingPage "529" @default.
- W2168951504 abstract "This paper is concerned with modeling the architecture of colonic crypts and the implications of this modeling for understanding possible coordinated response of carcinogen–induced DNA damage between various regions of the colon. The methods we develop to address these two issues are applied to a particular important example in colon carcinogenesis. We cast the problem as an unusual and not previously studied hierarchical mixed‐effects model characterized by completely missing covariates in units at a structurally base level, except for some randomly selected units. Information concerning the missing covariates is available through certain known ordering constraints and surrogate measures. Our methods use Bayesian machinery. We exploit the biological structure of this problem to generate the missing covariates simultaneously and efficiently at the base levels, as opposed to the naive practice of generating units at the base levels one‐at‐a‐time with Metropolis–Hastings steps. We apply our methods to show that different regions of the colon have different architectures, and to estimate an important but non‐standard function that measures the interrelationship of DNA damage mechanisms in different regions of the colon." @default.
- W2168951504 created "2016-06-24" @default.
- W2168951504 creator A5001295453 @default.
- W2168951504 date "2002-12-01" @default.
- W2168951504 modified "2023-09-23" @default.
- W2168951504 title "A Bayesian analysis of colonic crypt structure and coordinated response to carcinogen exposure incorporating missing crypts" @default.
- W2168951504 cites W1488005560 @default.
- W2168951504 cites W2044758663 @default.
- W2168951504 cites W2046798323 @default.
- W2168951504 cites W2056760934 @default.
- W2168951504 cites W2064414056 @default.
- W2168951504 cites W2070069066 @default.
- W2168951504 cites W2076967360 @default.
- W2168951504 cites W2117165767 @default.
- W2168951504 cites W2120350343 @default.
- W2168951504 cites W2130416410 @default.
- W2168951504 cites W2130811481 @default.
- W2168951504 cites W2138309709 @default.
- W2168951504 cites W2148534890 @default.
- W2168951504 cites W2149022033 @default.
- W2168951504 cites W2159309845 @default.
- W2168951504 cites W2170787360 @default.
- W2168951504 cites W2797508167 @default.
- W2168951504 cites W3023807737 @default.
- W2168951504 cites W3042168128 @default.
- W2168951504 doi "https://doi.org/10.1093/biostatistics/3.4.529" @default.
- W2168951504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12933596" @default.
- W2168951504 hasPublicationYear "2002" @default.
- W2168951504 type Work @default.
- W2168951504 sameAs 2168951504 @default.
- W2168951504 citedByCount "4" @default.
- W2168951504 countsByYear W21689515042014 @default.
- W2168951504 crossrefType "journal-article" @default.
- W2168951504 hasAuthorship W2168951504A5001295453 @default.
- W2168951504 hasBestOaLocation W21689515041 @default.
- W2168951504 hasConcept C107673813 @default.
- W2168951504 hasConcept C119043178 @default.
- W2168951504 hasConcept C119857082 @default.
- W2168951504 hasConcept C124101348 @default.
- W2168951504 hasConcept C134306372 @default.
- W2168951504 hasConcept C14036430 @default.
- W2168951504 hasConcept C154945302 @default.
- W2168951504 hasConcept C33923547 @default.
- W2168951504 hasConcept C38652104 @default.
- W2168951504 hasConcept C41008148 @default.
- W2168951504 hasConcept C42058472 @default.
- W2168951504 hasConcept C54355233 @default.
- W2168951504 hasConcept C66090201 @default.
- W2168951504 hasConcept C86803240 @default.
- W2168951504 hasConcept C9357733 @default.
- W2168951504 hasConceptScore W2168951504C107673813 @default.
- W2168951504 hasConceptScore W2168951504C119043178 @default.
- W2168951504 hasConceptScore W2168951504C119857082 @default.
- W2168951504 hasConceptScore W2168951504C124101348 @default.
- W2168951504 hasConceptScore W2168951504C134306372 @default.
- W2168951504 hasConceptScore W2168951504C14036430 @default.
- W2168951504 hasConceptScore W2168951504C154945302 @default.
- W2168951504 hasConceptScore W2168951504C33923547 @default.
- W2168951504 hasConceptScore W2168951504C38652104 @default.
- W2168951504 hasConceptScore W2168951504C41008148 @default.
- W2168951504 hasConceptScore W2168951504C42058472 @default.
- W2168951504 hasConceptScore W2168951504C54355233 @default.
- W2168951504 hasConceptScore W2168951504C66090201 @default.
- W2168951504 hasConceptScore W2168951504C86803240 @default.
- W2168951504 hasConceptScore W2168951504C9357733 @default.
- W2168951504 hasIssue "4" @default.
- W2168951504 hasLocation W21689515041 @default.
- W2168951504 hasLocation W21689515042 @default.
- W2168951504 hasOpenAccess W2168951504 @default.
- W2168951504 hasPrimaryLocation W21689515041 @default.
- W2168951504 hasRelatedWork W1984683132 @default.
- W2168951504 hasRelatedWork W2000280255 @default.
- W2168951504 hasRelatedWork W2057612738 @default.
- W2168951504 hasRelatedWork W2204166303 @default.
- W2168951504 hasRelatedWork W3032945164 @default.
- W2168951504 hasRelatedWork W3157819989 @default.
- W2168951504 hasRelatedWork W3192456749 @default.
- W2168951504 hasRelatedWork W3209240733 @default.
- W2168951504 hasRelatedWork W4297778181 @default.
- W2168951504 hasRelatedWork W2476934721 @default.
- W2168951504 hasVolume "3" @default.
- W2168951504 isParatext "false" @default.
- W2168951504 isRetracted "false" @default.
- W2168951504 magId "2168951504" @default.
- W2168951504 workType "article" @default.