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- W2168974169 abstract "In the context of mechanical loosening, we studied the hypothesis that wear-particle migration in the brous membrane under tibial plateaus after total knee arthroplasty can be explained by the pumping e!ects of the interstitial #uid in the tissue. Further, as a secondary objective we investigated the possibility that interface-tissue di!erentiation is in#uenced by interstitial #uid #ow and strain, as mechanical e!ects of interface motions. For comparative reasons, we analyzed a previously published simplied twodimensional nite-element model, this time assuming biphasic tissue properties. We wanted to determine hydrostatic pressure and #ow velocities in the#uid phase, in addition to stresses and strains, for time-dependent loading of the plateau. We found that #uid#ow in the interface was extremely slow, except in the periphery. Hence, loosening due to particle-induced bone resorption appears improbable. The results, however, do support the idea that particles migrate with #uid #ow, when such #ow occurs. Where brous tissue tends to be prominent in reality, the #uid is repeatedly extruded and reabsorbed in the model. Where these values are low, brocartilage is commonly found. When material properties were varied to subsequently represent brocartilage and two stages of mineralization, the strains and #uid velocities is reduced. Fluid pressure, however, did not change. Our results refute the hypothesis that wear particles are pumped through the interface tissue below a TKA but support the hypothesis that interface tissue type and loosening processes are in#uenced by mechanical tissue variables such as tissue strain and interstitial #uid velocity. ( 2000 Elsevier Science Ltd. All rights reserved." @default.
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- W2168974169 date "2000-01-01" @default.
- W2168974169 modified "2023-09-24" @default.
- W2168974169 title "Wear particle di!usion and tissue di!erentiation in TKA implant brous interfaces" @default.
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