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- W2168986192 abstract "Arteriolosclerosis (microvascular disease) may have a key role not only in driving salt-sensitive hypertension but also in mediating the development of chronic kidney disease, vascular dementia, stroke and coronary heart disease. In this paper, we review the evidence that these latter conditions result from the altered autoregulation that occurs when arterioles become diseased. We also discuss the increasing evidence that dietary intake of sugars rich in fructose may be driving the development of microvascular disease as a consequence of raising intracellular uric acid. We hypothesize that the treatment of microvascular disease may require a multifaceted approach by utilizing agents which aim at blocking of the renin–angiotensin system, reducing oxidative stress, stimulating endothelial nitric oxide production and lowering uric acid levels. Paradoxically, agents that only stimulate nitric oxide, such as oestrogens, may increase the risk of poor outcomes if microvascular disease is not reversed." @default.
- W2168986192 created "2016-06-24" @default.
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- W2168986192 date "2010-10-08" @default.
- W2168986192 modified "2023-10-18" @default.
- W2168986192 title "Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin" @default.
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- W2168986192 cites W1841074395 @default.
- W2168986192 cites W1963591576 @default.
- W2168986192 cites W1963700573 @default.
- W2168986192 cites W1966724309 @default.
- W2168986192 cites W1982261092 @default.
- W2168986192 cites W1985749449 @default.
- W2168986192 cites W2002849282 @default.
- W2168986192 cites W2007951064 @default.
- W2168986192 cites W2008444415 @default.
- W2168986192 cites W2009614218 @default.
- W2168986192 cites W2011413070 @default.
- W2168986192 cites W2012285157 @default.
- W2168986192 cites W2021678423 @default.
- W2168986192 cites W2022957257 @default.
- W2168986192 cites W2023547574 @default.
- W2168986192 cites W2024819549 @default.
- W2168986192 cites W2025372788 @default.
- W2168986192 cites W2026692048 @default.
- W2168986192 cites W2029182408 @default.
- W2168986192 cites W2030062071 @default.
- W2168986192 cites W2031005241 @default.
- W2168986192 cites W2033126909 @default.
- W2168986192 cites W2042994813 @default.
- W2168986192 cites W2043172105 @default.
- W2168986192 cites W2048892415 @default.
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- W2168986192 cites W2065486513 @default.
- W2168986192 cites W2067238258 @default.
- W2168986192 cites W2077202337 @default.
- W2168986192 cites W2090559153 @default.
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- W2168986192 cites W2103913904 @default.
- W2168986192 cites W2104681259 @default.
- W2168986192 cites W2105044392 @default.
- W2168986192 cites W2111277253 @default.
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- W2168986192 doi "https://doi.org/10.1093/ndt/gfq635" @default.
- W2168986192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20935013" @default.
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