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- W2169003222 abstract "A 20-year-old man presented with pitted keratolysis (PK), demonstrating the typical crateriform pits on the hallux ( Fig. 1), ball of the foot, and on the interdigital surface. The involved keratin specimen was obtained by a shaving technique and processed for transmission (TEM) and scanning (SEM) electron microscopy. The patient, who wore only sports shoes, had hyperhidrosis plantaris. He was treated with topical erythromycin with good results. Bacterial cultures from the lesions showed Corynebacterium sp. Figure 1Open in figure viewerPowerPoint Crateriform pits on the hallux TEM demonstrated filamentous coccoid bacteria in the keratin ( Fig. 2), showing transversal septations. Tunnel-like spaces were built inside the horny layer, where the bacteria showed a hairy surface ( Fig. 3). Figure 2Open in figure viewerPowerPoint Bacteria inside the stratum corneum (TEM, × 25,000) Figure 3Open in figure viewerPowerPoint Hairy surface from the causative agent (TEM, × 106,000) Crateriform pits ( Fig. 4) and small incipient lesions ( Fig. 5) were easily identified on the plantar surface by SEM. On examination of the floor of these lesions, tunnel openings were found ( Fig. 6) in which bacteria could be observed. With higher magnification, the transversal septation, seen by TEM, was also shown with SEM ( Fig. 7). The normal appearing plantar skin was also examined, showing incipient bacterial colonies with tunnels without keratin loss ( Fig. 8). Figure 4Open in figure viewerPowerPoint Pitted keratolysis with two incipient lesions on the right side (SEM, × 77.5) Figure 5Open in figure viewerPowerPoint Higher magnification of the incipient lesion from the right upper corner of Fig. 4 (SEM, × 310) Figure 6Open in figure viewerPowerPoint Tunnel openings in the floor of the pits (SEM, × 15,500) Figure 7Open in figure viewerPowerPoint Details of the bacteria; note the transversal septation (SEM, × 31,000) Figure 8Open in figure viewerPowerPoint The causative agent in tunnels in normal appearing skin (SEM, × 4650)" @default.
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- W2169003222 date "2000-09-01" @default.
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- W2169003222 title "Ultrastructure of pitted keratolysis" @default.
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- W2169003222 doi "https://doi.org/10.1046/j.1365-4362.2000.00035.x" @default.
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