FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169041305> ?p ?o ?g. }

• W2169041305 abstract "Background Current guidelines recommend that patients with peripheral arterial disease ( PAD ) cease smoking and be treated with aspirin, statin medications, and angiotensin‐converting enzyme ( ACE ) inhibitors. The combined effects of multiple guideline‐recommended therapies in patients with symptomatic PAD have not been well characterized. Methods and Results We analyzed a comprehensive database of all patients with claudication or critical limb ischemia ( CLI ) who underwent diagnostic or interventional lower‐extremity angiography between June 1, 2006 and May 1, 2013 at a multidisciplinary vascular center. Baseline demographics, clinical data, and long‐term outcomes were obtained. Inverse probability of treatment propensity weighting was used to determine the 3‐year risk of major adverse cardiovascular or cerebrovascular events ( MACE ; myocardial infarction, stroke, or death) and major adverse limb events ( MALE ; major amputation, thrombolysis, or surgical bypass). Among 739 patients with PAD , 325 (44%) had claudication and 414 (56%) had CLI . Guideline‐recommended therapies at baseline included use of aspirin in 651 (88%), statin medications in 496 (67%), ACE inhibitors in 445 (60%), and smoking abstention in 528 (71%) patients. A total of 237 (32%) patients met all four guideline‐recommended therapies. After adjustment for baseline covariates, patients adhering to all four guideline‐recommended therapies had decreased MACE (hazard ratio [ HR ], 0.64; 95% CI , 0.45 to 0.89; P =0.009), MALE ( HR , 0.55; 95% CI , 0.37 to 0.83; P =0.005), and mortality ( HR , 0.56; 95% CI , 0.38 to 0.82; P =0.003), compared to patients receiving less than four of the recommended therapies. Conclusions In patients with claudication or CLI , combination treatment with four guideline‐recommended therapies is associated with significant reductions in MACE , MALE , and mortality." @default.
• W2169041305 created "2016-06-24" @default.
• W2169041305 creator A5018260212 @default.
• W2169041305 creator A5027493221 @default.
• W2169041305 creator A5031798099 @default.
• W2169041305 creator A5033362539 @default.
• W2169041305 creator A5054013853 @default.
• W2169041305 creator A5064350034 @default.
• W2169041305 creator A5064848961 @default.
• W2169041305 creator A5069400507 @default.
• W2169041305 creator A5069460400 @default.
• W2169041305 creator A5082420041 @default.
• W2169041305 date "2014-03-24" @default.
• W2169041305 modified "2023-10-16" @default.
• W2169041305 title "Adherence to Guideline‐Recommended Therapy Is Associated With Decreased Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients With Peripheral Arterial Disease" @default.
• W2169041305 cites W108084996 @default.
• W2169041305 cites W1570622790 @default.
• W2169041305 cites W180946569 @default.
• W2169041305 cites W1840506659 @default.
• W2169041305 cites W1963481668 @default.
• W2169041305 cites W1965618515 @default.
• W2169041305 cites W1969363884 @default.
• W2169041305 cites W1995035040 @default.
• W2169041305 cites W1997286794 @default.
• W2169041305 cites W2004833857 @default.
• W2169041305 cites W2009187570 @default.
• W2169041305 cites W2011983013 @default.
• W2169041305 cites W2014336636 @default.
• W2169041305 cites W2020547160 @default.
• W2169041305 cites W2024352468 @default.
• W2169041305 cites W2028382800 @default.
• W2169041305 cites W2032626027 @default.
• W2169041305 cites W2040113464 @default.
• W2169041305 cites W2069882240 @default.
• W2169041305 cites W207639515 @default.
• W2169041305 cites W2082336558 @default.
• W2169041305 cites W2087242360 @default.
• W2169041305 cites W2106315724 @default.
• W2169041305 cites W2110101054 @default.
• W2169041305 cites W2116312562 @default.
• W2169041305 cites W2120827920 @default.
• W2169041305 cites W2122274177 @default.
• W2169041305 cites W2133184701 @default.
• W2169041305 cites W2140136269 @default.
• W2169041305 cites W2144985796 @default.
• W2169041305 cites W2150291618 @default.
• W2169041305 cites W2151793380 @default.
• W2169041305 cites W2155942116 @default.
• W2169041305 cites W2167067204 @default.
• W2169041305 cites W2172283319 @default.
• W2169041305 cites W2315630371 @default.
• W2169041305 cites W2346340950 @default.
• W2169041305 cites W2412772726 @default.
• W2169041305 cites W2572873578 @default.
• W2169041305 cites W2887712073 @default.
• W2169041305 cites W4233337036 @default.
• W2169041305 cites W424467158 @default.
• W2169041305 cites W4292320358 @default.
• W2169041305 cites W60172896 @default.
• W2169041305 doi "https://doi.org/10.1161/jaha.113.000697" @default.
• W2169041305 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4187469" @default.
• W2169041305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24721799" @default.
• W2169041305 hasPublicationYear "2014" @default.
• W2169041305 type Work @default.
• W2169041305 sameAs 2169041305 @default.
• W2169041305 citedByCount "179" @default.
• W2169041305 countsByYear W21690413052014 @default.
• W2169041305 countsByYear W21690413052015 @default.
• W2169041305 countsByYear W21690413052016 @default.
• W2169041305 countsByYear W21690413052017 @default.
• W2169041305 countsByYear W21690413052018 @default.
• W2169041305 countsByYear W21690413052019 @default.
• W2169041305 countsByYear W21690413052020 @default.
• W2169041305 countsByYear W21690413052021 @default.
• W2169041305 countsByYear W21690413052022 @default.
• W2169041305 countsByYear W21690413052023 @default.
• W2169041305 crossrefType "journal-article" @default.
• W2169041305 hasAuthorship W2169041305A5018260212 @default.
• W2169041305 hasAuthorship W2169041305A5027493221 @default.
• W2169041305 hasAuthorship W2169041305A5031798099 @default.
• W2169041305 hasAuthorship W2169041305A5033362539 @default.
• W2169041305 hasAuthorship W2169041305A5054013853 @default.
• W2169041305 hasAuthorship W2169041305A5064350034 @default.
• W2169041305 hasAuthorship W2169041305A5064848961 @default.
• W2169041305 hasAuthorship W2169041305A5069400507 @default.
• W2169041305 hasAuthorship W2169041305A5069460400 @default.
• W2169041305 hasAuthorship W2169041305A5082420041 @default.
• W2169041305 hasBestOaLocation W21690413051 @default.
• W2169041305 hasConcept C126322002 @default.
• W2169041305 hasConcept C127413603 @default.
• W2169041305 hasConcept C141071460 @default.
• W2169041305 hasConcept C142724271 @default.
• W2169041305 hasConcept C164705383 @default.
• W2169041305 hasConcept C197934379 @default.
• W2169041305 hasConcept C207103383 @default.
• W2169041305 hasConcept C2776204877 @default.
• W2169041305 hasConcept C2777466421 @default.
• W2169041305 hasConcept C2777628954 @default.
• W2169041305 hasConcept C2778963770 @default.
• W2169041305 hasConcept C2779464278 @default.

• next