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- W2169074414 abstract "The possible participation of oxytocin in the regulation of pituitary LtH secretion was studied by comparing the retarding effects of these hormones on mammary involution over a wide range of doses. Measurements of the content of nucleic acids and phosphoprotein and histological examinations of the mammary gland were performed. Vaginal smears were examined daily to check the effects of the treatments on luteal activity of the ovaries of the mother rats. Involution of the mammary glands after removing litters is retarded by administration of either oxytocin or LtH. The effect of oxytocin, however, seemed to differ considerably from that of LtH even at doses as small as 1.0 IU/day. The administration of oxytocin preserved only the structural integrity of the mammary tissue, which was reflected by DNA content and by the persistent alveolar structure. On the other hand, LtH injection not only prevented degeneration of tissue structure but also maintained functional activity. Recurrence of vaginal estrus and i..." @default.
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- W2169074414 date "1965-01-01" @default.
- W2169074414 modified "2023-10-05" @default.
- W2169074414 title "Relationship Between Oxytocin and Prolactin Secretion in Maintenance of Lactation in Rats" @default.
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- W2169074414 doi "https://doi.org/10.1210/endo-76-1-1" @default.
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