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• W2169116020 abstract "Background Intra‐individual variability reflects temporal variation within an individual's performance on a cognitive task. Children with developmental disorders, such as ADHD and ASD show increased levels of intra‐individual variability. In typical development, intra‐individual variability decreases sharply between the ages 6 and 20. The tight link between intra‐individual variability and age has led to the suggestion that it may be marker of neural development. As there is accumulating evidence that ADHD and ASD are characterised by atypical neurodevelopmental trajectories, we set out to explore developmental changes in intra‐individual variability in subjects with ADHD and ASD . Method We used propensity score matching to match a cross‐sectional sample of children with ADHD , ASD and control subjects ( N = 405, aged 6–19 years old) for age, IQ and gender. We used ex‐Gaussian distribution parameters to characterise intra‐individual variability on fast responses (sigma) and slow responses (tau). Result Results showed that there was a similar decrease in mean response times with age across groups, and an interaction between age and group for measures of variability, where there was a much lower rate of change in the variability parameters (sigma and tau) for subjects with ASD compared with the other two groups. Subjects with ADHD had higher intra‐individual variability, reflected by both sigma and tau, but the rate of decrease in variability with age was similar to that of the controls. Conclusion These results suggest that subjects with ADHD , ASD and controls differ in the rate at which intra‐individual variability decreases during development, and support the idea that intra‐individual variability may be a marker of neural development, mimicking the neurodevelopmental changes in these disorders." @default.
• W2169116020 created "2016-06-24" @default.
• W2169116020 creator A5008518522 @default.
• W2169116020 creator A5042728208 @default.
• W2169116020 creator A5061609800 @default.
• W2169116020 date "2015-04-13" @default.
• W2169116020 modified "2023-10-16" @default.
• W2169116020 title "Developmental differences in intra‐individual variability in children with <scp>ADHD</scp> and <scp>ASD</scp>" @default.
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• W2169116020 doi "https://doi.org/10.1111/jcpp.12417" @default.
• W2169116020 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25871802" @default.
• W2169116020 hasPublicationYear "2015" @default.
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