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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169120519> ?p ?o ?g. }

• W2169120519 endingPage "6309" @default.
• W2169120519 startingPage "6305" @default.
• W2169120519 abstract "We have constructed a Bacillus subtilis strain in which expression of a vanH::lacZ gene fusion is regulated by VanR and VanS of Enterococcus faecium. This construct allows a nonpathogenic bacterial strain to be used as a model system for studying regulation of vancomycin resistance. Antibiotics and enzymes that affect cell wall biosynthesis and stability were tested for the ability to induce lacZ expression. As a result, fosfomycin and D-cycloserine were added to the group of peptidoglycan synthesis inhibitors shown to induce expression from the vanH promoter. Induction by cell wall hydrolytic enzymes, as well as by antibiotics whose actions may lead to the accumulation of chemically different peptidoglycan precursors, raises the possibility that models that postulate induction by peptidoglycan [correction of peptidodoglycan] precursors are wrong." @default.
• W2169120519 created "2016-06-24" @default.
• W2169120519 creator A5044989625 @default.
• W2169120519 creator A5056230355 @default.
• W2169120519 creator A5074571324 @default.
• W2169120519 date "1996-11-01" @default.
• W2169120519 modified "2023-09-27" @default.
• W2169120519 title "A vancomycin-inducible lacZ reporter system in Bacillus subtilis: induction by antibiotics that inhibit cell wall synthesis and by lysozyme" @default.
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• W2169120519 doi "https://doi.org/10.1128/jb.178.21.6305-6309.1996" @default.
• W2169120519 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/178505" @default.
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