FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169169073> ?p ?o ?g. }

• W2169169073 endingPage "H828" @default.
• W2169169073 startingPage "H818" @default.
• W2169169073 abstract "We hypothesized that excessive sympathoactivation observed during strenuous exercise in subjects with heart failure (HF) may result from tonic activation of the muscle metaboreflex (MMR) via hypoperfusion of active skeletal muscle. We studied MMR responses in dogs during treadmill exercise by graded reduction of terminal aortic blood flow (TAQ) before and after induction of HF by rapid ventricular pacing. At a low workload, in both control and HF experiments, large decreases in TAQ were required to elicit the MMR pressor response. During control experiments, this pressor response resulted from increased cardiac output (CO), whereas in HF CO did not increase; thus the pressor response was solely due to peripheral vasoconstriction. In HF, MMR activation also induced higher plasma levels of vasopressin, norepinephrine (NE), and renin. At a higher workload, in control experiments any reduction of TAQ elicited MMR pressor responses. In HF, before any vascular occlusion, TAQ was already below MMR control threshold levels and reductions in TAQ again did not result in higher CO; thus SAP increased via peripheral vasoconstriction. NE rose markedly, indicating intense sympathetic activation. We conclude that in HF, the MMR is likely tonically active at moderate workloads and contributes to the tonic sympathoactivation." @default.
• W2169169073 created "2016-06-24" @default.
• W2169169073 creator A5026968678 @default.
• W2169169073 creator A5029212631 @default.
• W2169169073 creator A5034185938 @default.
• W2169169073 creator A5073092222 @default.
• W2169169073 creator A5085084737 @default.
• W2169169073 creator A5091611808 @default.
• W2169169073 date "2000-03-01" @default.
• W2169169073 modified "2023-10-16" @default.
• W2169169073 title "Heart failure alters the strength and mechanisms of the muscle metaboreflex" @default.
• W2169169073 cites W1759222371 @default.
• W2169169073 cites W1759262282 @default.
• W2169169073 cites W1766464384 @default.
• W2169169073 cites W1800390467 @default.
• W2169169073 cites W1837367668 @default.
• W2169169073 cites W1964836488 @default.
• W2169169073 cites W1986992048 @default.
• W2169169073 cites W2060789948 @default.
• W2169169073 cites W2070074309 @default.
• W2169169073 cites W2123921238 @default.
• W2169169073 cites W2153298916 @default.
• W2169169073 cites W2155306834 @default.
• W2169169073 cites W2163577314 @default.
• W2169169073 cites W2172993914 @default.
• W2169169073 cites W2227953569 @default.
• W2169169073 cites W2228828859 @default.
• W2169169073 cites W2232237980 @default.
• W2169169073 cites W2237192009 @default.
• W2169169073 cites W2256662442 @default.
• W2169169073 cites W2262501216 @default.
• W2169169073 cites W2270722068 @default.
• W2169169073 cites W2275644599 @default.
• W2169169073 cites W2320966627 @default.
• W2169169073 cites W2344994787 @default.
• W2169169073 cites W2398995882 @default.
• W2169169073 cites W2413010430 @default.
• W2169169073 cites W2416909131 @default.
• W2169169073 cites W2418731011 @default.
• W2169169073 cites W2441855739 @default.
• W2169169073 cites W34601894 @default.
• W2169169073 doi "https://doi.org/10.1152/ajpheart.2000.278.3.h818" @default.
• W2169169073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10710350" @default.
• W2169169073 hasPublicationYear "2000" @default.
• W2169169073 type Work @default.
• W2169169073 sameAs 2169169073 @default.
• W2169169073 citedByCount "106" @default.
• W2169169073 countsByYear W21691690732012 @default.
• W2169169073 countsByYear W21691690732013 @default.
• W2169169073 countsByYear W21691690732014 @default.
• W2169169073 countsByYear W21691690732015 @default.
• W2169169073 countsByYear W21691690732016 @default.
• W2169169073 countsByYear W21691690732017 @default.
• W2169169073 countsByYear W21691690732018 @default.
• W2169169073 countsByYear W21691690732019 @default.
• W2169169073 countsByYear W21691690732020 @default.
• W2169169073 countsByYear W21691690732021 @default.
• W2169169073 countsByYear W21691690732022 @default.
• W2169169073 countsByYear W21691690732023 @default.
• W2169169073 crossrefType "journal-article" @default.
• W2169169073 hasAuthorship W2169169073A5026968678 @default.
• W2169169073 hasAuthorship W2169169073A5029212631 @default.
• W2169169073 hasAuthorship W2169169073A5034185938 @default.
• W2169169073 hasAuthorship W2169169073A5073092222 @default.
• W2169169073 hasAuthorship W2169169073A5085084737 @default.
• W2169169073 hasAuthorship W2169169073A5091611808 @default.
• W2169169073 hasConcept C126322002 @default.
• W2169169073 hasConcept C134018914 @default.
• W2169169073 hasConcept C146957229 @default.
• W2169169073 hasConcept C164705383 @default.
• W2169169073 hasConcept C2778198053 @default.
• W2169169073 hasConcept C2779961880 @default.
• W2169169073 hasConcept C71924100 @default.
• W2169169073 hasConceptScore W2169169073C126322002 @default.
• W2169169073 hasConceptScore W2169169073C134018914 @default.
• W2169169073 hasConceptScore W2169169073C146957229 @default.
• W2169169073 hasConceptScore W2169169073C164705383 @default.
• W2169169073 hasConceptScore W2169169073C2778198053 @default.
• W2169169073 hasConceptScore W2169169073C2779961880 @default.
• W2169169073 hasConceptScore W2169169073C71924100 @default.
• W2169169073 hasIssue "3" @default.
• W2169169073 hasLocation W21691690731 @default.
• W2169169073 hasLocation W21691690732 @default.
• W2169169073 hasOpenAccess W2169169073 @default.
• W2169169073 hasPrimaryLocation W21691690731 @default.
• W2169169073 hasRelatedWork W1966504330 @default.
• W2169169073 hasRelatedWork W1979139803 @default.
• W2169169073 hasRelatedWork W2020128704 @default.
• W2169169073 hasRelatedWork W2030889776 @default.
• W2169169073 hasRelatedWork W2037631372 @default.
• W2169169073 hasRelatedWork W2040058909 @default.
• W2169169073 hasRelatedWork W2132898409 @default.
• W2169169073 hasRelatedWork W2748952813 @default.
• W2169169073 hasRelatedWork W4249176446 @default.
• W2169169073 hasRelatedWork W2171560843 @default.
• W2169169073 hasVolume "278" @default.
• W2169169073 isParatext "false" @default.
• W2169169073 isRetracted "false" @default.

• next