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- W2169173314 abstract "Babesia parasites generally require a defined percentage of serum in the culture medium for their in vitro growth. In this study, we attempted to culture Babesia bovis in a serum-free condition. The growth pattern and morphology of B. bovis in serum-free (plain) GIT medium were unaltered as compared to those of the standard growth condition containing 40% bovine serum in M199. When exposed to the test drugs, the parasite in plain GIT medium showed clearly lower IC50 values than those in 40% serum-containing G IT medium, indicating that several serum components may interfere with the drug bio-availability. Therefore, the serum-free culture system is useful for standardizing drug test protocols and understanding the roles of serum factors in the drug test." @default.
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- W2169173314 date "2005-05-01" @default.
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- W2169173314 title "Host serum modifies the drug susceptibility of Babesia bovis in vitro" @default.
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- W2169173314 doi "https://doi.org/10.1017/s0031182004006821" @default.
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