Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169195383> ?p ?o ?g. }
- W2169195383 endingPage "598" @default.
- W2169195383 startingPage "592" @default.
- W2169195383 abstract "Liver transplantation is often the ultimate option of therapy for chronically hepatitis B virus (HBV) infected patients. Adoptive transfer of HBV immunity with the liver after vaccination of living liver donors (LLD) could be a new approach to prevent reinfection in the recipients. The time to achieve HBV immunity in LLD is usually short (1-2 months). Therefore, we established a short time immunization protocol (four injections in 2 weeks intervals) using Hepimmune, a recombinant vaccine that contains the L, M and S proteins of HBV. We examined cellular and humoral immune responses after immunization with Hepimmune and compared its immunogenicity to that of a standard HBV vaccine containing only the S protein (HBVAXPRO). Cellular immunity was measured by interferon (IFN)-gamma ELISpot and proliferation assay. HBV-specific T cells were detectable in the Hepimmune group after the second and in the standard group after the third vaccination. IFN-gamma production of T cells was significantly higher (P < 0.001) after the third vaccination with Hepimmune. Proliferative responses were also significantly (P < 0.01) higher in the Hepimmune group after the second to fourth vaccination. The humoral immune response could already be detected after the first immunization in nine of 15 Hepimmune vaccinated test persons while it was only observed in one of 15 probands of the later group. Titres differed significantly (P < 0.01) following all four vaccinations. Thus, Hepimmune appears to be a good candidate for short time immunization protocols." @default.
- W2169195383 created "2016-06-24" @default.
- W2169195383 creator A5034134992 @default.
- W2169195383 creator A5042895787 @default.
- W2169195383 creator A5044001706 @default.
- W2169195383 creator A5059338299 @default.
- W2169195383 creator A5082162455 @default.
- W2169195383 creator A5089789550 @default.
- W2169195383 date "2007-04-30" @default.
- W2169195383 modified "2023-10-18" @default.
- W2169195383 title "Cellular and humoral immune response to a third generation hepatitis B vaccine" @default.
- W2169195383 cites W1590593271 @default.
- W2169195383 cites W1672765421 @default.
- W2169195383 cites W1967398623 @default.
- W2169195383 cites W1967653443 @default.
- W2169195383 cites W1967700144 @default.
- W2169195383 cites W1974163737 @default.
- W2169195383 cites W1979409884 @default.
- W2169195383 cites W1984472078 @default.
- W2169195383 cites W2017184316 @default.
- W2169195383 cites W2017970545 @default.
- W2169195383 cites W2020757435 @default.
- W2169195383 cites W2022424341 @default.
- W2169195383 cites W2024912322 @default.
- W2169195383 cites W2030237079 @default.
- W2169195383 cites W2040293663 @default.
- W2169195383 cites W2044794182 @default.
- W2169195383 cites W2047083308 @default.
- W2169195383 cites W2056504757 @default.
- W2169195383 cites W2061594530 @default.
- W2169195383 cites W2061734833 @default.
- W2169195383 cites W2064554898 @default.
- W2169195383 cites W2074792024 @default.
- W2169195383 cites W2074959616 @default.
- W2169195383 cites W2076058883 @default.
- W2169195383 cites W2083547267 @default.
- W2169195383 cites W2091712885 @default.
- W2169195383 cites W2093809510 @default.
- W2169195383 cites W2094575100 @default.
- W2169195383 cites W2096811431 @default.
- W2169195383 cites W2118520230 @default.
- W2169195383 cites W2120128540 @default.
- W2169195383 cites W2122440054 @default.
- W2169195383 cites W2128445804 @default.
- W2169195383 cites W2132243512 @default.
- W2169195383 cites W2146295449 @default.
- W2169195383 cites W2170308370 @default.
- W2169195383 cites W2318639814 @default.
- W2169195383 cites W2338794667 @default.
- W2169195383 cites W4237323099 @default.
- W2169195383 cites W84554624 @default.
- W2169195383 doi "https://doi.org/10.1111/j.1365-2893.2007.00848.x" @default.
- W2169195383 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17650294" @default.
- W2169195383 hasPublicationYear "2007" @default.
- W2169195383 type Work @default.
- W2169195383 sameAs 2169195383 @default.
- W2169195383 citedByCount "29" @default.
- W2169195383 countsByYear W21691953832012 @default.
- W2169195383 countsByYear W21691953832013 @default.
- W2169195383 countsByYear W21691953832014 @default.
- W2169195383 countsByYear W21691953832015 @default.
- W2169195383 countsByYear W21691953832016 @default.
- W2169195383 countsByYear W21691953832017 @default.
- W2169195383 countsByYear W21691953832018 @default.
- W2169195383 countsByYear W21691953832021 @default.
- W2169195383 crossrefType "journal-article" @default.
- W2169195383 hasAuthorship W2169195383A5034134992 @default.
- W2169195383 hasAuthorship W2169195383A5042895787 @default.
- W2169195383 hasAuthorship W2169195383A5044001706 @default.
- W2169195383 hasAuthorship W2169195383A5059338299 @default.
- W2169195383 hasAuthorship W2169195383A5082162455 @default.
- W2169195383 hasAuthorship W2169195383A5089789550 @default.
- W2169195383 hasConcept C159047783 @default.
- W2169195383 hasConcept C203014093 @default.
- W2169195383 hasConcept C22070199 @default.
- W2169195383 hasConcept C2522874641 @default.
- W2169195383 hasConcept C2776090121 @default.
- W2169195383 hasConcept C2776548049 @default.
- W2169195383 hasConcept C2777382497 @default.
- W2169195383 hasConcept C2777410769 @default.
- W2169195383 hasConcept C2779053233 @default.
- W2169195383 hasConcept C2779341262 @default.
- W2169195383 hasConcept C2780593183 @default.
- W2169195383 hasConcept C2780801004 @default.
- W2169195383 hasConcept C2780868878 @default.
- W2169195383 hasConcept C2781037505 @default.
- W2169195383 hasConcept C3017875465 @default.
- W2169195383 hasConcept C71924100 @default.
- W2169195383 hasConcept C8891405 @default.
- W2169195383 hasConceptScore W2169195383C159047783 @default.
- W2169195383 hasConceptScore W2169195383C203014093 @default.
- W2169195383 hasConceptScore W2169195383C22070199 @default.
- W2169195383 hasConceptScore W2169195383C2522874641 @default.
- W2169195383 hasConceptScore W2169195383C2776090121 @default.
- W2169195383 hasConceptScore W2169195383C2776548049 @default.
- W2169195383 hasConceptScore W2169195383C2777382497 @default.
- W2169195383 hasConceptScore W2169195383C2777410769 @default.
- W2169195383 hasConceptScore W2169195383C2779053233 @default.