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- W2169221210 endingPage "275" @default.
- W2169221210 startingPage "267" @default.
- W2169221210 abstract "The radical SAM superfamily of enzymes catalyzes a broad spectrum of biotransformations by employing a common obligate intermediate, the 5′-deoxyadenosyl radical (DOA). Radical formation occurs via the reductive cleavage of S-adenosylmethionine (SAM or AdoMet). The resultant highly reactive primary radical is a potent oxidant that enables the functionalization of relatively inert substrates, including unactivated C–H bonds. The reactions initiated by the DOA are breathtaking in their efficiency, elegance and in many cases, the complexity of the biotransformation achieved. This review describes the common features shared by enzymes that generate the DOA and the intriguing variations or modifications that have recently been reported. The review also highlights selected examples of the diverse biotransformations that ensue." @default.
- W2169221210 created "2016-06-24" @default.
- W2169221210 creator A5091814568 @default.
- W2169221210 date "2011-04-01" @default.
- W2169221210 modified "2023-10-03" @default.
- W2169221210 title "Radicals from S-adenosylmethionine and their application to biosynthesis" @default.
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- W2169221210 cites W1993478007 @default.
- W2169221210 cites W1996711495 @default.
- W2169221210 cites W1998953863 @default.
- W2169221210 cites W2004939146 @default.
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- W2169221210 doi "https://doi.org/10.1016/j.cbpa.2010.11.015" @default.
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