Matches in SemOpenAlex for { <https://semopenalex.org/work/W2169231479> ?p ?o ?g. }
- W2169231479 endingPage "402" @default.
- W2169231479 startingPage "393" @default.
- W2169231479 abstract "Film autoradiography was used to investigate the expression of several neurotransmitter receptor subtypes in the transient ventricular and subventricular proliferative zones of the developing occipital lobe in two groups of macaque monkey fetuses. The first group of fetuses were between 60 and 93 days after conception (E60-E93), when the ventricular and subventricular zones of the monkey occipital lobe produce neurons destined for the visual cortex. In the second group, fetuses were between E107 and E128, after generation of cortical neurons has ceased. In the E60–E93 group of fetuses, ventricular and subventricular zones displayed high densities of 5-HT1-serotonergic, D1-dopaminergic, α1-and α2-adrenergic and high affinity kainate receptors. The activation of these receptors has previously been shown to stimulate cell proliferation in other cell systems. The possible involvement of these receptors in regulation of neuronal production is also supported by their absence in the deep laminae of the embryonic cerebral wall after E107, after cortical neurogenesis has been completed. The only exception is a high density of α2-adrenergic receptors maintained near the ventricular surface long after all cortical neurons have been generated. We also found that during neurogenesis, proliferative zones in E66–E90 fetuses displayed virtually no 5-HT2-serotonergic, D2-dopaminergic, β-adrenergic, M1-muscarinic cholinergic, gamma aminobutyric acid (GABA)A, N-methyl-D-aspartate (NMDA), or β-amino-3-hydroxy-5-menthy-4-isoxazole proprionate (AMPA) sites; most of these receptor subtypes have been reported to mediate the suppression of cell proliferation. The present findings suggest that dividing and/or newly generated cortical neurons are capable of receiving specific signals from multiple neurotransmitters present in their environment. © 1995 Wiley-Liss, Inc." @default.
- W2169231479 created "2016-06-24" @default.
- W2169231479 creator A5038455977 @default.
- W2169231479 creator A5073325036 @default.
- W2169231479 date "1995-09-25" @default.
- W2169231479 modified "2023-09-23" @default.
- W2169231479 title "Neurotransmitter receptors in the proliferative zones of the developing primate occipital lobe" @default.
- W2169231479 cites W1503175985 @default.
- W2169231479 cites W1519825607 @default.
- W2169231479 cites W1612454610 @default.
- W2169231479 cites W1966653793 @default.
- W2169231479 cites W1971096666 @default.
- W2169231479 cites W1977033986 @default.
- W2169231479 cites W1977464020 @default.
- W2169231479 cites W1979952856 @default.
- W2169231479 cites W1980869466 @default.
- W2169231479 cites W1985142350 @default.
- W2169231479 cites W1990625157 @default.
- W2169231479 cites W1991164196 @default.
- W2169231479 cites W2000735704 @default.
- W2169231479 cites W2001671746 @default.
- W2169231479 cites W2002214235 @default.
- W2169231479 cites W2003850081 @default.
- W2169231479 cites W2004910932 @default.
- W2169231479 cites W2010049654 @default.
- W2169231479 cites W2011762562 @default.
- W2169231479 cites W2014112598 @default.
- W2169231479 cites W2021195752 @default.
- W2169231479 cites W2025809696 @default.
- W2169231479 cites W2026924604 @default.
- W2169231479 cites W2037722939 @default.
- W2169231479 cites W2041024256 @default.
- W2169231479 cites W2054072520 @default.
- W2169231479 cites W2054758465 @default.
- W2169231479 cites W2055144184 @default.
- W2169231479 cites W2061888513 @default.
- W2169231479 cites W2062883936 @default.
- W2169231479 cites W2064310011 @default.
- W2169231479 cites W2067804507 @default.
- W2169231479 cites W2068629141 @default.
- W2169231479 cites W2071785245 @default.
- W2169231479 cites W2072185504 @default.
- W2169231479 cites W2072723883 @default.
- W2169231479 cites W2073075937 @default.
- W2169231479 cites W2074683128 @default.
- W2169231479 cites W2080558320 @default.
- W2169231479 cites W2081656169 @default.
- W2169231479 cites W2081966783 @default.
- W2169231479 cites W2082922514 @default.
- W2169231479 cites W2084029736 @default.
- W2169231479 cites W2086586202 @default.
- W2169231479 cites W2098917377 @default.
- W2169231479 cites W2102409931 @default.
- W2169231479 cites W2130793535 @default.
- W2169231479 cites W2134358071 @default.
- W2169231479 cites W2158901548 @default.
- W2169231479 cites W2171037148 @default.
- W2169231479 cites W232827651 @default.
- W2169231479 cites W4229635074 @default.
- W2169231479 cites W68470042 @default.
- W2169231479 doi "https://doi.org/10.1002/cne.903600303" @default.
- W2169231479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8543647" @default.
- W2169231479 hasPublicationYear "1995" @default.
- W2169231479 type Work @default.
- W2169231479 sameAs 2169231479 @default.
- W2169231479 citedByCount "63" @default.
- W2169231479 countsByYear W21692314792013 @default.
- W2169231479 countsByYear W21692314792015 @default.
- W2169231479 countsByYear W21692314792016 @default.
- W2169231479 countsByYear W21692314792017 @default.
- W2169231479 countsByYear W21692314792018 @default.
- W2169231479 countsByYear W21692314792019 @default.
- W2169231479 crossrefType "journal-article" @default.
- W2169231479 hasAuthorship W2169231479A5038455977 @default.
- W2169231479 hasAuthorship W2169231479A5073325036 @default.
- W2169231479 hasConcept C126322002 @default.
- W2169231479 hasConcept C134018914 @default.
- W2169231479 hasConcept C136834591 @default.
- W2169231479 hasConcept C156927020 @default.
- W2169231479 hasConcept C160268369 @default.
- W2169231479 hasConcept C169760540 @default.
- W2169231479 hasConcept C170493617 @default.
- W2169231479 hasConcept C189184402 @default.
- W2169231479 hasConcept C2775864247 @default.
- W2169231479 hasConcept C2777542384 @default.
- W2169231479 hasConcept C28328180 @default.
- W2169231479 hasConcept C37000724 @default.
- W2169231479 hasConcept C4746552 @default.
- W2169231479 hasConcept C61174792 @default.
- W2169231479 hasConcept C71924100 @default.
- W2169231479 hasConcept C86803240 @default.
- W2169231479 hasConcept C95444343 @default.
- W2169231479 hasConceptScore W2169231479C126322002 @default.
- W2169231479 hasConceptScore W2169231479C134018914 @default.
- W2169231479 hasConceptScore W2169231479C136834591 @default.
- W2169231479 hasConceptScore W2169231479C156927020 @default.
- W2169231479 hasConceptScore W2169231479C160268369 @default.
- W2169231479 hasConceptScore W2169231479C169760540 @default.