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• W2169231801 abstract "Depression and anxiety and are associated with cognitive deficits and brain changes, especially in older adults. Despite the frequent co-occurrence of these conditions, cognitive neuroscience studies examining comorbid depression and anxiety are limited. The goal of the present study was to examine the unique and combined effect of depressive and anxiety symptoms on cognitive and brain functioning in young and older adults.Seventy-one healthy, community-dwelling adults between the ages of 18 and 81 were administered a neuropsychological battery and completed the Center for Epidemiologic Studies Depression Scale (CES-D) and the trait form of the State-Trait Anxiety Inventory (STAI-T). A subset of 25 participants also underwent functional magnetic resonance imaging (fMRI) scanning while completing the n-back working memory task.Total depressive symptoms, depressed mood symptoms, and somatic symptoms were associated with deficits in speed, working memory and executive functions, especially in older adults. Symptoms of lack of well-being were not associated with any neuropsychological test. Anxiety was associated with better attention and working memory. Moreover, anxiety modified the relationship between depressive symptoms and executive functioning in older adults, as elevated depressive symptoms were associated with worse performance at low levels of anxiety, but not at higher anxiety levels. Similarly, analysis of fMRI data showed that total depressive symptoms and depressed mood symptoms were associated with decreased activity in the superior frontal gyrus at low anxiety levels, but not at high anxiety levels.Results confirm previous reports that subthreshold depression and anxiety impact cognitive and brain functioning and suggest that the interaction of depression and anxiety results in distinct cognitive and brain changes. Findings highlight the importance of assessing and controlling for symptoms of depression and anxiety in research studies of either condition." @default.
• W2169231801 created "2016-06-24" @default.
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• W2169231801 creator A5077749466 @default.
• W2169231801 creator A5080787549 @default.
• W2169231801 date "2014-01-01" @default.
• W2169231801 modified "2023-10-09" @default.
• W2169231801 title "Unique and Interactive Effect of Anxiety and Depressive Symptoms on Cognitive and Brain Function in Young and Older Adults" @default.
• W2169231801 cites W132371621 @default.
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• W2169231801 cites W1510212850 @default.
• W2169231801 cites W1590852549 @default.
• W2169231801 cites W1665095741 @default.
• W2169231801 cites W1959299669 @default.
• W2169231801 cites W1964640782 @default.
• W2169231801 cites W1964851255 @default.
• W2169231801 cites W1965148737 @default.
• W2169231801 cites W1968626800 @default.
• W2169231801 cites W1969686278 @default.
• W2169231801 cites W1969709016 @default.
• W2169231801 cites W1972717007 @default.
• W2169231801 cites W1976155541 @default.
• W2169231801 cites W1979345194 @default.
• W2169231801 cites W1983475921 @default.
• W2169231801 cites W1984623076 @default.
• W2169231801 cites W1986429531 @default.
• W2169231801 cites W1988537390 @default.
• W2169231801 cites W1991602278 @default.
• W2169231801 cites W1991880588 @default.
• W2169231801 cites W1992416557 @default.
• W2169231801 cites W1992474739 @default.
• W2169231801 cites W1993391176 @default.
• W2169231801 cites W1994069965 @default.
• W2169231801 cites W1994911542 @default.
• W2169231801 cites W1994947322 @default.
• W2169231801 cites W1996881939 @default.
• W2169231801 cites W2005190428 @default.
• W2169231801 cites W2008257099 @default.
• W2169231801 cites W2010734852 @default.
• W2169231801 cites W2016409713 @default.
• W2169231801 cites W2026460712 @default.
• W2169231801 cites W2031940914 @default.
• W2169231801 cites W2034199982 @default.
• W2169231801 cites W2037457456 @default.
• W2169231801 cites W2039122324 @default.
• W2169231801 cites W2040909768 @default.
• W2169231801 cites W2044569637 @default.
• W2169231801 cites W2046357922 @default.
• W2169231801 cites W2048997923 @default.
• W2169231801 cites W2049549817 @default.
• W2169231801 cites W2052713078 @default.
• W2169231801 cites W2054434123 @default.
• W2169231801 cites W2057227102 @default.
• W2169231801 cites W2060923304 @default.
• W2169231801 cites W2062063364 @default.
• W2169231801 cites W2068302579 @default.
• W2169231801 cites W2068403333 @default.
• W2169231801 cites W2070890774 @default.
• W2169231801 cites W2074246284 @default.
• W2169231801 cites W2080243976 @default.
• W2169231801 cites W2083501849 @default.
• W2169231801 cites W2093220018 @default.
• W2169231801 cites W2098307144 @default.
• W2169231801 cites W2098743205 @default.
• W2169231801 cites W2101800098 @default.
• W2169231801 cites W2102039394 @default.
• W2169231801 cites W2108337682 @default.
• W2169231801 cites W2111609296 @default.
• W2169231801 cites W2113440025 @default.
• W2169231801 cites W2115859056 @default.
• W2169231801 cites W2140852353 @default.
• W2169231801 cites W2142360036 @default.
• W2169231801 cites W2143814803 @default.
• W2169231801 cites W2148003144 @default.
• W2169231801 cites W2162394665 @default.
• W2169231801 cites W2164382381 @default.
• W2169231801 cites W2167061609 @default.
• W2169231801 cites W2169366712 @default.
• W2169231801 cites W2170701421 @default.
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• W2169231801 doi "https://doi.org/10.4172/2167-1044.s1-003" @default.
• W2169231801 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4222514" @default.
• W2169231801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25383262" @default.
• W2169231801 hasPublicationYear "2014" @default.
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