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- W2169242103 abstract "We have reported that D-Fraction extracted from maitake (Grifola frondosa), activates immune competent cells, and indicates anti-tumor activities. The D-Fraction was observed to induce angiogenesis in vivo and to enhance the proliferation capability and migration capability of human vascular endothelial cell in vitro. The D-Fraction also increased plasma vascular endothelial growth factor (VEGF) concentration significantly. Also VEGF and TNF-alpha production by the activated peritoneal macrophages were enhanced. These results suggest that the anti-tumor activity of the D-Fraction is not only associated with the activation of the immuno-competent cells but also possibly related to the carcinoma angiogenesis induction." @default.
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- W2169242103 date "2001-10-01" @default.
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- W2169242103 title "Effects of Maitake ( Grifola frondosa ) D-Fraction on the carcinoma angiogenesis" @default.
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- W2169242103 doi "https://doi.org/10.1016/s0304-3835(01)00652-8" @default.
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