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• W2169289946 endingPage "14" @default.
• W2169289946 startingPage "1" @default.
• W2169289946 abstract "Abstract Bone is a composite material that combines both organic and inorganic phases into a complex structure with extraordinary mechanical properties. Numerous synthetic systems have been developed and are under investigation to create composites for the fabrication of both fixation devices and templates for the repair and regeneration of bone tissue. In the case of tissue engineering, the development of new scaffolds able to support and stimulate cell ingrowth and differentiation is of main importance. In this context, parameters such as the material nature, its physical and chemical properties as well as the structural and morphological properties of the 3D constructs are of paramount importance for the successful outcome of the scaffold‐based tissue engineering approach. A wide range of natural and synthetic polymers as well as numerous fabrication techniques have been used in the development of new 3D scaffolds for the regeneration of bone tissue. In this article, a comprehensive overview of the different materials and methods used for the elaboration of these structures is given as well as a thorough description of the role and relevance of the surface properties of materials and their implications in the biological response." @default.
• W2169289946 created "2016-06-24" @default.
• W2169289946 creator A5001208673 @default.
• W2169289946 creator A5034383745 @default.
• W2169289946 date "2012-07-20" @default.
• W2169289946 modified "2023-10-14" @default.
• W2169289946 title "Composite Scaffolds for Bone Tissue Regeneration" @default.
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